If you're considering targeted therapy cost in 2025, you're likely facing a range of emotions, from hope for better treatment outcomes to worry about affordability. Targeted therapy offers effective cancer treatment with fewer side effects, but the cost can be overwhelming, up to $30,000 per month in the USA, especially without the right insurance coverage. At Bookimed, we've conducted in-depth research and compiled the latest updates with verified information on targeted therapy costs for 2025. Let’s explore what to expect and how you can save on this crucial treatment, whether you’re exploring options abroad or navigating insurance challenges associated with the therapy. ▶️

❗ This page may feature information relating to various medical conditions, treatments, and healthcare services available in different countries. Please be advised that the content is provided for informational purposes only and should not be construed as medical advice or guidance. Please consult with your doctor or a qualified medical professional before starting or changing medical treatment.

✅ Key Takeaways

  • Targeted therapy is a precise, effective cancer treatment, but costs vary widely by country and drug type.

  • In 2025, prices range from $15,000 in Israel to $30,000+ per month in the U.S.

  • Affordable, high-quality care is available in Turkey, Thailand, Germany, Italy, and Israel.

  • Lutetium-177 therapy is showing 30–40% tumor reduction in select patients.

  • Costs depend on drug type, diagnostics, insurance, and treatment length.

  • Bookimed helps patients navigate options, compare prices, and organize treatment abroad — completely free of charge.

Table of Contents

  1. How Much Does Standard Targeted Therapy Cost?
  2. What’s Included in a Standard Targeted Therapy Package?
  3. Factors Influencing the Cost of Targeted Therapy
  4. What Countries Offer the Most Affordable Targeted Therapy Options?
  5. Targeted Therapy Insurance Options
  6. Tips on How to Save on Targeted Therapy
  7. Success Stories and Patient Reviews
  8. FAQs
  9. Conclusion

How Much Does Standard Targeted Therapy Cost?

Quote:

The Targeted Cancer Therapy Market was valued at USD 16.55 Billion in 2024, and is expected to reach USD 25.24 Billion by 2030, rising at a CAGR of 7.25%”

Business Wire (Dublin) Press Release, June 06, 2025.

The cost of targeted therapy for cancer varies widely. According to the latest reports from the Cancer Therapy Advisor, in 2025, the United States had the highest costs, with monthly treatments often exceeding $27,000.

In Canada, prices are generally lower, from $3,000 to $4,000, and provincial coverage helps reduce out-of-pocket expenses, as confirmed by the data available in the National Library of Medicine associated with the National Institutes of Health.

Australia benefits from PBS subsidies, which lower treatment costs that may initially range from $5,000 to $11,000, according to data provided by the Australian Prescriber.

In Germany, the estimated monthly cost is approximately $5,900 USD.

Turkey offers targeted therapy at an estimated cost of $2,500 USD per month.

In Thailand, the cost ranges from $3,150 to $3,500 USD per month.

Italy has a broader range, with costs ranging from €70,000 to €78,000 over the course of treatment, while in Israel, the average cost is around $15,000 to $30,000.

These variations reflect differences in healthcare systems, subsidies, and the cost of living in each country, offering patients various options based on their budget and location preferences.

To help you better understand the costs of targeted therapy in different countries, we have provided a detailed comparison of monthly treatment prices across various types of targeted therapy, based on the latest data provided by the Cancer Council NSW. This table provides a clearer picture of what to expect when seeking a particular targeted therapy treatment type in 2025:

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Targeted Therapy Type USA Canada Australia Germany Turkey Thailand Italy Israel
Monoclonal Antibodies
(e.g., Lutetium-177 therapy)
$8,000–$12,000 $8,000–$12,000 $8,000–$12,000 $25,000–$40,000 $8,000–$12,000 $3,500 $8,000–$15,000 $20,000–$35,000
Small-Molecule Drugs $17,000–$18,000 $14,000–$17,000 $14,000–$18,000 $12,000–$18,000 $8,000–$12,000 $3,500 $10,000–$15,000 $15,000–$25,000
Angiogenesis Inhibitors $20,000–$35,000 $15,000–$30,000 $4,000–$6,000 $20,000–$40,000 $3,000–$11,500 $3,500 $12,000–$25,000 $20,000–$35,000
Signal Transduction Inhibitors $17,000–$18,000 $14,000–$17,000 $14,000–$18,000 $15,000–$25,000 $5,000–$15,000 $3,500 $13,000–$22,000 $15,000–$25,000
Proteasome Inhibitors $4,000–$8,000 $4,000–$8,000 $4,000–$8,000 $4,000–$8,000 $2,500–$7,000 $2,500–$5,000 $4,000–$8,000 $4,000–$8,000
Monoclonal Antibody-Drug Conjugates $10,000–$30,000 $10,000–$30,000 $10,000–$30,000 $10,000–$30,000 $5,000–$12,000 $3,500–$7,000 $10,000–$30,000 $15,000–$25,000

If these therapy types, terms, and numbers seem complicated, don’t worry! You can always contact a Bookimed coordinator for detailed explanations, personalized information about targeted therapy packages, and options available in specific countries or hospitals. Our team is here to guide you through the process and help you find the best and most affordable treatment options. It’s free for patients.

Now, let’s move on to explore what’s typically included in a standard targeted therapy package to help you understand exactly what to expect from your treatment. ▶️

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38 years of experience
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Nuclear medicine physician - Cuneyt Turkmen
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What’s Included in a Standard Targeted Therapy Package?

As reported by the National Cancer Institute (NCI), a standard targeted therapy package for cancer treatment includes:

  • targeted drugs;
  • personalized diagnostics;
  • tailored administration methods.

The cost of targeted therapy for cancer can vary based on factors such as the type of drug, country, and treatment duration.

Monoclonal antibodies, particularly Lutetium-177 therapy and small-molecule inhibitors, are standard therapies included, each designed to precisely target cancer cells while minimizing side effects.

A regular targeted therapy package typically includes the following components, designed to deliver precision cancer treatment:

1. Targeted Drug(s) 🎯

The core of any targeted therapy package is the targeted drug. These may include:

Targeted Therapy Type Description
Small-molecule inhibitors 💊 These drugs, such as tyrosine kinase inhibitors, target specific proteins involved in cancer cell growth and survival.
Monoclonal antibodies 🧬 Recognize and bind to specific proteins on cancer cells or in the tumor environment, blocking growth signals or marking cancer cells for immune destruction.
Antibody-drug conjugates (ADCs) 💉 Combine antibodies with toxic drugs to deliver chemotherapy directly to cancer cells, increasing efficacy and minimizing toxicity to healthy cells.

2. Administration Method 💉

Depending on the specific treatment, targeted therapies may be administered via infusions, injections, or oral medications taken at home. The method of administration and the therapy’s duration can significantly influence the overall targeted therapy cost. For instance, therapies given intravenously in a hospital setting are usually more expensive than oral treatments taken at home.

3. Diagnostic Testing 🔬

Before treatment begins, molecular or genetic tests are typically performed to identify specific mutations or protein expressions in the patient’s tumor cells. These tests help determine which targeted therapy is most likely to be effective. Personalized testing ensures that each patient receives the most appropriate treatment, optimizing the outcome.

4. Treatment Monitoring and Support 🩺

Ongoing clinical monitoring is essential to assess the treatment response and manage any side effects. This may include blood tests and imaging, along with supportive care to handle any adverse reactions. This care is particularly important for ensuring that any potential complications, such as fluid accumulation or infection, are caught early and treated effectively.

5. Tailored Treatment Schedule 📅

Targeted therapies are often delivered in cycles or as continuous dosing regimens, depending on the type of cancer and how the patient responds. The length of treatment can vary, and monitoring is critical to adjust dosing as needed. The targeted therapy success rate can improve with a carefully tailored schedule.

This comprehensive approach offers precision oncology care, maximizing the therapy's effectiveness while minimizing harm to healthy cells.

❗ If you'd like to know what’s included in a particular targeted therapy package at a clinic that has caught your attention, a Bookimed coordinator is always here to help. We’re happy to answer all your questions and provide detailed information to help you make an informed decision. This assistance is provided completely free of charge to patients.

Now, let’s dive into the factors influencing the cost of targeted therapy, so you can better understand the pricing and make the best decision for your treatment. ▶️

Factors Influencing the Cost of Targeted Therapy

According to the data provided in the Comparative Report on Cancer in Europe in 2025, by the European Federation of Pharmaceutical Industries and Associations (EFPIA), the cost of targeted therapy is influenced by various factors, including:

  • the type of therapy;
  • drug manufacturing costs;
  • patient-specific factors.

Other key aspects, such as:

  • diagnostic testing;
  • treatment duration;
  • combination therapies can also drive costs.
  • furthermore, healthcare system regulations, market dynamics, and geographic location contribute to the overall cost of targeted cancer treatment in different regions.

The cost of targeted cancer therapy is influenced by several key factors:

1. Type and Complexity of Targeted Therapy 💊

The price can vary significantly based on the type of therapy. For instance, the Dove Medical Press reports that small-molecule inhibitors, such as tyrosine kinase inhibitors, tend to be less expensive than more complex biologics, including monoclonal antibodies and antibody-drug conjugates (ADCs). ADCs, in particular, are costly due to their intricate manufacturing process and the combination of antibodies with cytotoxic drugs.

2. Drug Development and Manufacturing Costs 🏗️

The cost of targeted therapies is also driven by the advanced techniques used in drug development, such as molecular targeting and biologic production, as well as the growing field of personalized medicine.

3. Diagnostic and Molecular Testing 🔬

Prior to treatment, precise genetic or molecular tests (e.g., next-generation sequencing) are necessary to identify cancer mutations and ensure the therapy is suited to the patient’s needs. This testing adds additional costs before the treatment begins.

4. Treatment Regimen and Combination Therapies 💉

When targeted therapies are combined with treatments like chemotherapy or immunotherapy, the overall costs rise due to the added expense of extra drugs and managing potential side effects.

5. Treatment Duration and Dosing ⏳

The length of therapy and the frequency of dosing also play a significant role in determining the cost. Ongoing or long-term treatments lead to higher overall expenses.

6. Healthcare System and Reimbursement Policies 🏥

Factors that influence the targeted therapy costs.

National healthcare systems, insurance coverage, and drug pricing regulations also influence the amount patients pay out of pocket, as noted in the Comparative Report on Cancer in Europe (2025). Managed entry agreements and government subsidies may impact overall treatment costs.

7. Market Dynamics and Price Trends 📈

The cost of targeted therapies has increased significantly in many regions, often outpacing inflation. As the Cancer Therapy Advisor suggests, this rise is driven by factors such as patent protections, limited competition, and price optimization strategies by manufacturers.

8. Side Effect Management and Monitoring 🩺

Regular monitoring and supportive care to manage side effects from targeted therapies contribute to additional costs beyond the drug price itself.

  • Geographic and Economic Variability 🌍
    Cost variations are significant across countries due to differences in local healthcare systems, drug pricing, purchasing power, and the availability of generic or biosimilar alternatives, as noted by the Comparative Report on Cancer in Europe (2025).

In summary, the cost of targeted therapy in 2025 is influenced by the complexity of the therapy, diagnostic testing, treatment protocols, healthcare policies, and regional economic conditions. Patients seeking effective and high-quality targeted therapy treatment must consider all these factors to ensure the best possible outcomes.

Now, let's explore the countries that offer the most affordable targeted therapy options. This will help you make an informed decision, taking into account both quality and cost. ▶️

What Countries Offer the Most Affordable Targeted Therapy Options?

According to Bookimed data, these countries offer affordable targeted therapy options, especially for international patients seeking medical tourism opportunities. The most cost-effective destinations include:

1. 🇩🇪 Germany

Looking for affordable targeted therapy in Europe? Germany offers top-tier cancer treatment using the latest precision medicine at costs often lower than in the U.S. or the UK. Patients choose Germany for its high standards, experienced oncologists, and advanced technology. Bookimed helps organize treatment in certified cancer centers quickly and easily. Trusted by thousands of patients worldwide

According to Bookimed data, clinics in Germany are certified by KTQ (Cooperation for Transparency and Quality in Healthcare), confirming their compliance with strict standards in patient safety and medical quality. German oncology centers apply advanced diagnostic tools like Next-Generation Sequencing (NGS) to tailor treatment plans. They also use targeted drugs, including monoclonal antibodies developed by global leaders such as Roche and Novartis, ensuring precise and individualized therapy..

In Germany, the average cost of targeted therapy is around $5,900 per course, ranging $3,500–$9,300, based on official data from partner clinics. By contrast, the U.S. average launch price for recent targeted drugs ranges from $173,000 to $240,000 per year. The average targeted therapy costs range around €6,000 per course

Germany’s median cancer‑drug price in the last decade averaged $37,650, compared to about $74,200 in the U.S. Clinics such as Asklepios Hospital Barmbek and Medical Center in Solingen follow ESMO and NCCN guidelines, offering molecular diagnostics and modern targeted regimens at a more affordable rate.

Asklepios Hospital Barmbek
Germany, Hamburg
89% patients recommend

Asklepios Oncology Centers perform targeted therapy for treatment of different types of cancer. It is a new treatment option achieving high recovery rates even at the advanced stages. Oncologists develop targeted therapy regimen for each patient. Then doctors administer specific drugs in the veins of a patient. The procedure is performed on outpatient basis.

The targeted therapy ‘recognizes’ malignant tumors protein and blocks the biochemical reactions in the tumor. As a result, cancer cells stop dividing and die. The therapy also stimulates the immune system to detect cancer cells. The targeted therapy affects only malignant cells without affecting healthy tissues.

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International Organization for Standardization certificate for Asklepios Hospital Barmbek Medical Travel Quality Alliance certificate for Asklepios Hospital Barmbek TOP German hospital according to 2019 Focus ranking certificate for Asklepios Hospital Barmbek

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My father was suffering from pulmonary related disease , after doing study about medical tourism agents. I have decided to prepare my father medical treatment in Germany by Bookimed as this agency as per my experience is the best agency in terms of organizing medical treatment for patient across the globe is the best option for everyone which i suggest for each patient . From Bookimed Dr Younus and Lydia from Talvin organise my father medical treatment in Germany, they have recommended Asklepios Hospital in Hamburg which is one of the top hospital in Germany , my father treatment was done by Dr Gunther Wiest. My father was too much satisfied with the Dr treatment along with rich experience the Dr behaviour was sweet with my father due which my father was much satisfied and inspired from him. Overall our experience with Bookimed and Dr treatment was excellent.
— Sadiq jahan
Pakistan, Apr 18, 2022
Apr 18, 2022 • Verified review.
Targeted therapy $3495.27 - $9320.73
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Medical Center in Solingen
Germany, Solingen
93% patients recommend

Solingen Clinic for Oncology specializes in the treatment of different types of cancer. Oncologists prescribe a targeted therapy regimen if chemotherapy is ineffective or when it can show better results. Targeted therapy can be used without surgery or other treatment options. It is effective for skin, colorectal, blood, lung, kidney cancer, etc.

The mechanism of targeted therapy is the following: specific drugs administered into the body detect the protein of cancer cells. Then they are recognized, medications block the development of biochemical processes inside the tumor. As a result, malignant cells stop their growth and die.

Compared to chemotherapy, targeted therapy does not destroy healthy tissues, so a quantity of side effects is much lower.

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Best doctor for herniated disc treatment certificate for Medical Center in Solingen German Cancer Society certificate for Medical Center in Solingen

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Having made an initial enquiry on line, I was impressed by the follow up and treatment proposals and costs I did some research and determined that I needed to get the very best medical attention It was a great help to have somebody with me during the day of the tests, sorting my papers and dealing with translation. Absolutely invaluable Everything was explained to me in detail My only comments are that it would have been good to have been informed about the number of nights stay in the hospital I expected an overnight stay after the procedure In fact for good reasons it was a total of three nights
— Jeremy
United Kingdom, Mar 30, 2025
Mar 30, 2025 • Verified review.
4.6
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Asklepios St. Georg Hospital
Germany, Hamburg
68% patients recommend
  • Ranked among the TOP 100 medical centers in Germany by Focus magazine since 2015.
  • Houses a Research Center of Hamburg University, developing innovative targeted therapy methods.
  • Has 18 awards and certificates confirming high-quality medical services, including targeted therapy.
  • Offers a comprehensive range of targeted therapy options through its 25 departments.
  • Serves 87,000 patients annually, demonstrating extensive experience in patient care.
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Everything is high. The doctor came before the operation (did ablation) and said that it gives 99%, which will be a good result. Chamber for one person, everything you need is there, everything is thought out. Coordinator Pavel answered all my questions very promptly.
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Russian Federation, Dec 19, 2018
Dec 19, 2018 • Verified review.
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2. 🇹🇷 Turkey

Targeted therapy in Turkey achieves a 70–80% effectiveness rate in improving outcomes for specific cancer types, especially when based on genetic testing and molecular profiling (ESMO). In Turkey, treatment is performed by skilled oncologists like Prof. Dr. Yasemin Altuner Torun and Assoc. Prof. Dr. Tahsin Ozatli, who has years of experience and manages hundreds of cancer cases annually. Patients have access to advanced targeted therapy options in trusted, internationally accredited clinics.

Need effective targeted therapy at a lower cost? Turkey offers modern oncology services—including targeted drugs approved under international protocols—at significantly reduced prices. Clinics in Istanbul, Bursa, Antalya, and Sivas follow ESMO and NCCN guidelines and earn JCI accreditation. With Bookimed’s support, you get transparent pricing, trusted clinics, and personal coordination from start to finish.

In Turkey, the average cost of targeted therapy is around $3,020 (range: $1,000–$5,000), based on verified partner clinics in Istanbul, Bursa, and Antalya, including Anadolu Medical Center, Memorial Şişli, Liv Hospital, and Istinye University Bahcesehir, all JCI‑accredited centers following international standards. Compared to U.S. annual targeted drug prices (often exceeding $170,000 to $240,000) and median cancer‑drug launch prices (~$74,200), Turkey offers comparable precision care at a fraction of the cost.

Anadolu Medical Center
Turkey, Istanbul
92% patients recommend

The specialists of Anadolu Medical Oncology Department prescribe a targeted therapy for treatment of some types of cancer. It shows good results even at the advanced stages of oncological development. Oncologists prescribe a targeted therapy regimen. Specialized medical staff inserts the medications into a patient’s body. Such drugs can be used: bevacizumab, cetuximab (Erbitux), panitumumab (Vectibix).

Targeted therapy affects only malignant cells without destroying healthy ones as chemo does. According to this, targeted therapy has fewer side effects and complications, while the result is better. Oncologists can prescribe targeted therapy as the only treatment options. The procedure is provided on the outpatient basis.

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International Organization for Standardization certificate for Anadolu Medical Center Joint Commission International  certificate for Anadolu Medical Center European Society for Medical Oncology certificate for Anadolu Medical Center Organisation of European Cancer Institutes Certificate certificate for Anadolu Medical Center  Johns Hopkins Medicine certificate for Anadolu Medical Center Patient Choice for Basic Check-up certificate for Anadolu Medical Center Patient choice in Oncology & Hematology Oncology certificate for Anadolu Medical Center International Accreditation System for Interventional Oncology Services (IASIOS) certificate for Anadolu Medical Center  Planetree's Gold Certificate certificate for Anadolu Medical Center

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I had a very positive experience at Anadolu Hospital in Istanbul. Everything was very well organized, and I was especially impressed by the professionalism and kindness of the assistants, the translator, and most of all, the doctors. I truly felt supported and well taken care of throughout the process. I would like to extend a special thank you to Mrs. Meriem for her exceptional assistance — her help was truly invaluable. If I may offer one small remark, it would be that the brain MRI report was a bit limited in detail. Aside from that, everything was impeccable. I am very satisfied and grateful for the care I received. Thank you again to the entire team!
— Hind Bensekrane
Turkey, Jul 4, 2025
Jul 4, 2025 • Verified review.
4.6
Targeted therapy $3000 - $5000
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Memorial Şişli Hospital
Turkey, Istanbul
91% patients recommend
  • Oncology Department follows NCCN and ESMO protocols for targeted therapy management.
  • Specialists perform targeted drugs specifically to destroy cancer cells accurately.
  • Equipped with TrueBeam STx and IMRT devices for precise tumor irradiation.
  • International patients from 92 countries choose Memorial Şişli annually.
  • Oncology Department offers specialized support to minimize therapy side effects.
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Having breast reduction and uplift surgery is something that I had wanted for numerous years but due to underlying health conditions I knew it wouldn't be straight forward. When I eventually made the decision I couldn't have made a better decision. From the initial contact and liason s from Bookimed to the transfers, hotel, hospital tests, surgery and post surgery support was more than I could have asked for. The interpreter Bayza was exceptional and made me feel relaxed throughout the process. The hospital staff and especially my surgeon Dr Kadriye who was so friendly and professional throughout. I honestly had an amazing experience. All my health issues were taken very seriously and accommodated for by giving me the relevant tests and aftercare. I would advise from my personal experience to take clothes that button or unzip after surgery .And my must have item would be my neck cushion that I took with me for after surgery for when you have to sleep upright. Memorial Sisli was outstanding. And I am so happy with outcome. Thankyou all . The photos were from the morning of surgery and the 7th day after.
— Amanda Kirby
United Kingdom, Jul 26, 2025
Jul 26, 2025 • Verified review.
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Memorial Bahçelievler Hospital
Turkey, Istanbul
89% patients recommend
  • Achieved a 99% success rate in kidney transplants, reflecting expertise in precise medical procedures like targeted therapy.
  • Offers targeted therapy options, with advanced equipment such as the Elekta Versa HD SIGNATURE for precise tumor targeting.
  • Dr. Sadi Kerem Okutur leads targeted therapy with over 20 years of oncology experience and numerous research contributions.
  • Memorial Bahçelievler is the first hospital in Turkey with a LEED Platinum certificate, ensuring a comfortable, eco-friendly environment.
  • Provides comprehensive international patient services, including personal coordinators and medical interpreters for seamless treatment experiences.
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Very good, but I'd come back for a stay of more than 3 days as it's too short to make an assessment. If you don't want to be in a hurry, you need to plan for 5 days on site, preferably outside the weekend! The doctors are extremely competent, attentive and relevant! The hospital is magnificent, large and clean. It has all the technology you need, and despite the wait, I highly recommend memoriall!
— Sabrina Zoughli
France, Apr 29, 2025
Apr 29, 2025 • Verified review.
4.6
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3. 🇹🇭 Thailand

Thailand offers accessible targeted cancer therapy in internationally recognized clinics, often at much lower cost than Western countries, starting from $3,500. Facilities such as Bumrungrad International Hospital use FDA‑approved targeted drugs, follow ESMO protocols, and support fast scheduling with no waitlists. Bookimed coordinates your care process, providing transparent pricing and personalized assistance through trusted Thai hospitals.

In Thailand, targeted therapy is available from clinics ranked among the Top‑10 worldwide for advanced oncology care, delivering treatment packages that cost 35–75% less than equivalent procedures done separately. The Bumrungrad International Hospital in Bangkok serves over 1 million patients yearly, half of them international, and is known for its use of innovative targeted inhibitors and the IBM Watson for Oncology system to support treatment planning. While exact prices are quoted upon request, this location offers cost-effective targeted therapy with short stays, efficient service, and high patient satisfaction.

Bumrungrad International Hospital
Thailand, Bangkok
91% patients recommend
  • Ranked among the world's TOP-10 hospitals and TOP-30 most technologically advanced clinics for targeted therapy.
  • Utilizes innovative targeted cancer inhibitors approved by the US FDA for personalized cancer treatment plans.
  • Employs IBM Watson for Oncology to enhance treatment accuracy and minimize medical errors in targeted therapy.
  • No waiting lists, allowing timely access to targeted therapy with a global patient base from 190 countries.
  • Offers cost-effective treatment packages, saving patients 35-75% compared to separate procedures.
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Thank you very much to Anna from Bookmed, who organized an online consultation for my husband, she is a very responsive and kind person. She answered me at any time, the time difference was big. Thanks a lot! The doctor said that the diagnosis was good and we finally calmed down. The doctor waited until the MRI was loaded and rescheduled the appointment
— Banu
Kazakhstan, Dec 2, 2023
Dec 2, 2023 • Verified review.
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4. 🇮🇹 Italy

Targeted therapy in Italy shows an efficacy rate of 75–85%, depending on the cancer type, leading to notable improvements in treatment outcomes. Oncology teams include board-certified specialists, many recognized by the European Society for Medical Oncology (ESMO). With more than 5,000 cases performed, these experts bring extensive experience in delivering personalized, evidence-based cancer care.

Italy delivers affordable targeted cancer therapy in internationally accredited hospitals like San Raffaele in Milan. Approved medications are applied under ESMO guidelines and modern diagnostic protocols. Patients benefit from transparent pricing, streamlined logistics, and expert care. Bookimed helps coordinate your treatment across trusted clinics, simplifying every step from appointment booking to follow-up.

In Italy, targeted therapy packages start from around €70,000-78,000 over the course of treatment in centres such as San Raffaele Hospital in Milan, which follows international oncology standards.

San Raffaele is JCI-accredited and known for high standards in molecular diagnostics and precision oncology. Compared to U.S. targeted drug prices—often exceeding $170,000 per year—Italy offers effective treatments at a considerably lower cost while maintaining safety and quality of care.

San Raffaele
Italy, Milan
85% patients recommend

Ospedale San Raffaele (San Raffaele Research Hospital) in Milan is one of the largest research hospitals in Europe. It applies ad hoc methods for rare immune system and genetic diseases treatment.

Among its achievements — the world's first stem cell therapy for patients with severe combined immune deficiency disorder (ADA-SCID).

Oncology, oncohematology, neurosurgery, neurology, cardiovascular surgery, urology, and gynecology are the strongest specialities here.

Surgeons of the hospital perform over 52,000 operations annually.

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I was very impressed by eveything.It took us almost 6 months to find the best doctor and Hospital for my mum.The agent who helped us from bookimed was the best lots of research and we finally settelled for st Rafaella Hospital .We were not disappointed Everything was done well and perfectly and the Agent was intouch all the way through it all.I would recommend anyone to go through them.My mother got. her Treatment and we are very greatful.It was a very stressful time knowing that my mother had to go for radioiodine for her thyroid turns out she did not need that and that there was other Options available .We are thankful.
— Anonymous
Switzerland, Jan 20, 2025
Jan 20, 2025 • Verified review.
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5. ISR Israel

Top Israeli clinics offering targeted therapy include Sourasky Medical Center (Ichilov) in Tel Aviv and Sheba Medical Center in Ramat Gan—both JCI-accredited institutions known for their high standards of cancer care. These hospitals apply advanced targeted treatments, including HER2 inhibitors and genome-based therapies, aligned with international protocols. Targeted therapy in Israel shows a 75–90% effectiveness rate, depending on the cancer type and molecular characteristics. The cost typically starts from $750 per course, with pricing varying based on the:

  • type of drug;
  • diagnostics;
  • treatment duration.

Oncologists such as Dr. David Sarid, Dr. Ofer Merimsky, and Dr. Pelles Sharon bring decades of experience and have successfully treated thousands of patients using modern precision oncology tools.Israel delivers effective targeted cancer therapy at competitive prices compared to Western countries. Top hospitals like Sourasky (Ichilov) and Sheba Medical Center follow international oncology standards and use trusted drugs like HER2‑targeted therapies. Patients benefit from high success rates and coordinated care through Bookimed, ensuring transparent pricing and fast scheduling in English-speaking, JCI‑accredited institutions.

In Israel, targeted therapy shows an average efficacy of 75–90% across various cancer types. Treatment costs typically start from around $750 per course and may include diagnostics, hospital stay, and follow-up care. Bookimed’s leading medical centers, such as Sourasky Medical Center (Ichilov) in Tel Aviv and Sheba Medical Center in Ramat Gan, are JCI‑accredited and offer modern techniques, including HER2 inhibitors and genome-based treatments. Oncologists at these hospitals have treated thousands of patients successfully.

Sourasky Medical Center (Ichilov)
Israel, Tel Aviv
83% patients recommend

Oncologists of Sourasky Oncology Department apply targeted therapy for cancer treatment. It is alternative to chemotherapy for treatment skin, blood, stomach, lung, kidney, prostate cancers. Specialists administer medications in a patient’s organism. They detect malignant cells and destroys them, stop their division and help the immune system to ‘recognize’ cancer.

Oncologists appoint targeted therapy only after a complete examination of a patient. The main advantage of this therapy compared to chemo is that it does not affect healthy cells, only cancer affected ones. Targeted therapy also causes fewer side effects. It does not require hospitalization or additional treatment options.

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Hospital certificates and accreditation of quality

World's Best Smart Hospitals 2021 by Newsweek certificate for Sourasky Medical Center (Ichilov) World's Best Hospitals 2021 by Newsweek certificate for Sourasky Medical Center (Ichilov) World's Best Hospitals 2020 by Newsweek certificate for Sourasky Medical Center (Ichilov) Patient choice for Check-up certificate for Sourasky Medical Center (Ichilov) Fastest treatment organization certificate for Sourasky Medical Center (Ichilov) Joint Commission International  certificate for Sourasky Medical Center (Ichilov) World's Best Specialized Hospitals 2022 by Newsweek certificate for Sourasky Medical Center (Ichilov) World's Best Smart Hospitals 2023 by Newsweek certificate for Sourasky Medical Center (Ichilov) World's Best Hospitals 2022 by Newsweek certificate for Sourasky Medical Center (Ichilov)

Latest review

Verified review.
We received a detailed consultation with Dr. Pelles Sharon and her assistant Denis. They explained everything, gave me a treatment plan, and the doctor was very attentive to details. We are very grateful for the small chance that these doctors gave us. I would also like to note the work of the coordinator, Yulia. A very sensitive, empathetic specialist, she was able to organize everything quickly. Thanks a lot!
— Stanislav
Belarus, Jan 31, 2024
Jan 31, 2024 • Verified review.
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Assuta Medical Center
Israel, Tel Aviv
91% patients recommend

Doctors of Assuta Medical Center apply a wide range of treatment options. Among them is targeted therapy. It is an innovative therapy which is used instead of chemotherapy and surgery. Targeted therapy supposes the administration of drugs into a patient’s organism through the veins. Doctors conduct this procedure on an outpatient basis.

Inserted medications find the malignant cells and stop their development. After a while, these cells die. If chemotherapy inhibits both healthy and malignant cells, targeted therapy does only cancer. So this treatment option is safer for a patient and does not cause severe side effects.

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Hospital certificates and accreditation of quality

Joint Commission International  certificate for Assuta Medical Center

Latest review

Verified review.
Hello, I had 2 melanomas detected, they cut me out, then I found this clinic on the Internet, I applied because I had an ultrasound of the lymph nodes in my groin and under my arm. They met me at the clinic, took me to Dr. Bernstein’s office, and the ultrasound showed good results, thank you very much, good service, I am satisfied.
— Anonymous
Israel, Mar 6, 2020
Mar 6, 2020 • Verified review.
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Hadassah Medical Center
Israel, Jerusalem
83% patients recommend

Hadassah Medical Center is a state multi-specialty medical center located in Jerusalem, Israel. The strongest specialties are neurosurgery, orthopedics, oncology, and hematology oncology. Every year, over 150 Hadassah doctors are included in the TOP of the best doctors by Forbes magazine. Hadassah Medical Center serves both adults and children. 1,000,000 patients choose Hadassah Medical Center to get medical care every year. Patients from CIS, Europe & Commonwealth and Arab League States visit the clinic most often. In 2017, Melania Trump, former First Lady of the USA, visited Hadassah Medical Center as a leading Israeli hospital.

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Hospital certificates and accreditation of quality

Nobel Peace Prize certificate for Hadassah Medical Center World's Best Hospitals 2021 by Newsweek certificate for Hadassah Medical Center World's Best Smart Hospitals 2021 by Newsweek certificate for Hadassah Medical Center

Latest review

Verified review.
Hello! My husband was treated at the University Hospital Hadassah. He has liver cancer. He is extremely impressed with the quality of medical care, the attention of professors Daniel Shuval, Alan Bloom, Ayal Hubert and their colleagues. He is grateful for the care of him. We had the opportunity to choose treatment in 5 leading hospitals in the world. And we are glad that by choosing HADASS we made the best and the right choice. Because this hospital has world-class medical care. But this would not have happened if it had not been for the wonderful organization and work of the specialists from the International Department who have been helping us all the time. With all my heart I thank everyone who helped and continues to help Pavel Kalchev in his fight against cancer. I wish all HADASS specialists health. Health for their families. Ivelina Krustinkova Bulgaria
— Ивелина
Bulgaria, Feb 28, 2020
Feb 28, 2020 • Verified review.
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Country What is it? Benefits Limitations Clinical Results Session Duration Recovery Process Most Effective For Cost
Germany A form of precision radiotherapy that uses the Lutetium‑177 isotope to target and destroy specific cancer cells. Delivers radiation directly to tumor cells. Not effective for all cancers. For responsive patients, treatment can shrink tumors by 30–40%. Each procedure typically lasts 1 to 2 hours. Full recovery: a few weeks, depending on individual response. Prostate cancer with matching receptor characteristics.
 $5,900 USD
Turkey A targeted form of radiotherapy that uses the Lutetium‑177 isotope to treat certain cancers with precision. Clinical response seen in 60% of patients with neuroendocrine tumors. Requires careful patient evaluation due to possible kidney-related side effects. For responsive patients, treatment can shrink tumors by 30–40%. Each procedure typically lasts 1 to 2 hours. Full recovery: a few weeks, depending on individual response. Neuroendocrine tumors. Prostate cancer with matching receptor characteristics.
$2,500 USD
Thailand Targeted radiotherapy using Lutetium‑177 radioisotope for cancer treatment. High precision — minimizes damage to healthy tissues. This procedure requires strict patient selection and kidney function monitoring. Tumor size reduced by 30–40% in responsive patients. 1–2 hours per session. Initial recovery: 1–2 days
Full recovery: a few weeks
Neuroendocrine tumors. Prostate cancer with specific receptor expression. $3,020
Israel A targeted radiotherapy that uses the Lutetium‑177 isotope to treat specific cancers with precision. High precision with minimal harm to healthy tissues. 60% of patients with neuroendocrine tumors respond positively. Not suitable for all cancer types. Requires careful monitoring due to potential kidney toxicity. Achieves 30–40% reduction in tumor size in responsive patients. 1–2 hours per session. Initial recovery: 1–2 days
Full recovery: a few weeks
Neuroendocrine tumors. Prostate cancer with specific receptor expression.
 $170,000 per year
 
Italy A form of targeted radiotherapy using the Lutetium‑177 isotope to treat selected cancers with accuracy. Minimizes damage to healthy tissues; 60% response rate in neuroendocrine tumor cases. Not suitable for all cancers. Requires strict monitoring due to possible kidney toxicity. Tumor size reduction of 30–40% in responsive patients. Typically lasts 1–2 hours. Initial recovery: 1–2 days
Full recovery: a few weeks
Neuroendocrine tumors. Prostate cancer with specific receptor expression.
 €70,000-78,000 over the course

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Targeted Therapy Insurance Options

Insurance coverage for targeted therapy can vary significantly depending on your provider, country of residence, and the specific treatment plan. Start by contacting your insurance company to confirm which therapies and drugs are covered, especially if they are newer or high-cost. Ask about pre-authorization requirements, documentation, and whether genetic testing needed for drug selection is included.

If you’re seeking treatment abroad or at a specialized center, check the policy’s out-of-network coverage. Some insurers may partially reimburse treatment if it's considered medically necessary and unavailable locally.

Another option is to explore clinical trials, which may cover the cost of the drug, testing, and sometimes even travel expenses. Trials can be found on platforms like clinicaltrials.gov.

For those without adequate coverage, pharmaceutical assistance programs, hospital financial counselors, or Bookimed’s coordination support may help reduce expenses and streamline access to therapy.

Several major insurance companies now offer coverage for targeted therapy, though inclusion varies by region and policy. Here are two prominent examples and the general rules for accessing targeted therapy through them:

  1. Prudential (Example: PRUCancer X plan) 🛡️💳
    Prudential's PRUCancer X plan provides coverage for targeted cancer therapies, along with surgery, chemotherapy, and radiotherapy. The plan may offer a payout of up to RM2 million. To access this benefit, patients should consult both their doctor and a Prudential agent to confirm eligibility and ensure all required documentation—such as proof of medical necessity and a physician’s recommendation—is submitted correctly for claim approval.

  2. Aviva (UK private health insurance) 📋🧾
    Aviva includes full coverage for targeted therapy as part of its standard cancer benefits, alongside chemotherapy and radiotherapy. To qualify, the therapy must be officially licensed for the specific cancer type and recommended as clinically necessary by the treating oncologist. If a patient opts for treatment under the UK’s National Health Service (NHS) instead, they may be eligible for a cash benefit in place of direct treatment coverage. It's also essential to confirm whether outpatient services are included in the plan, especially if the therapy is administered outside a hospital setting.

Navigating insurance coverage for targeted therapy requires careful planning and clear communication with your provider. Whether you’re receiving treatment locally or abroad, knowing what’s covered—and exploring options like clinical trials or patient assistance programs—can make these advanced therapies more accessible. If you're unsure where to start, Bookimed's team can help you understand your options and connect you with trusted medical centers, free of charge.

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Tips on How to Save on Targeted Therapy 🧑‍⚕️💬💰

Tips How To Save On Targer

To save on targeted therapy,Bookimed recommends starting by optimizing your insurance coverage and exploring available patient assistance programs. Ask about biosimilars or generic alternatives to reduce drug costs, and consider participating in clinical trials for access to cutting-edge therapies at no cost or for reduced fees. Additionally, consider specialty pharmacies and medical tourism options for more affordable treatments in select countries.

Here are more detailed, practical tipsto help you save on targeted therapy costs:

1. Understand and Optimize Your Insurance Coverage 💼

Navigating insurance policies can be overwhelming, especially when dealing with a cancer diagnosis. However, understanding the details of your coverage is one of the most effective ways to reduce out-of-pocket expenses for targeted therapy. By taking a proactive approach, you can uncover potential benefits and avoid unexpected costs:

  • Review your insurance plan carefully to determine if it covers targeted therapies, including any applicable co-pays and coverage limits. If your therapy is denied, you can appeal with support from your physician.
  • Ask about financial navigator services offered by cancer centers or insurance providers to help you make the most of your insurance benefits.

As you see, saving on targeted therapy is possible with the right approach—by understanding your insurance, exploring assistance programs, and considering lower-cost treatment options abroad. Bookimed is here to help you navigate these choices and find affordable, high-quality care at no extra cost.

2. Explore Patient Assistance Programs (PAPs) and Charities 💰

According to the American Cancer Society,pharmaceutical companies often offer co-pay assistance or free drug programs. Many nonprofits, such as the Leukemia & Lymphoma Society, also offer financial aid for treatment and related expenses like travel or lodging.

3. Use Generic or Biosimilar Alternatives When Available 💊

Discuss with your oncologist whether generic or biosimilar drugs could be used as substitutes for brand-name targeted therapies. The American Association for Cancer Research (AACR) claims this can significantly lower your costs without sacrificing effectiveness.

4. Participation in Clinical Trials 🎯

The National Medical Association (NMA) recommends considering enrollment in clinical trials, which may offer access to cutting-edge, targeted therapies at reduced or no cost, including treatment, diagnostics, and sometimes even travel support.

5. Coordinate Care Through Specialty Pharmacies 🏥

According to reports by Healthline, specialty pharmacies can help source medications at negotiated prices, assist with insurance paperwork, and improve adherence hereby making therapy more affordable, t.

6. Consider Treatment Location and Medical Tourism Options 🌍

The cost of targeted therapies can vary by location. Some countries, like Turkey or Thailand, offer advanced treatments at a fraction of the cost found in Western countries. However, be sure to factor in travel and follow-up care expenses.

7. Optimize Treatment Regimens and Diagnostics 🧬

Work with your healthcare team to avoid unnecessary tests and imaging. Efficient diagnostics and dose adjustments can help reduce out-of-pocket costs while still ensuring effective treatment.

8. Leverage Discount Cards and Manufacturer Coupons 💳

Some pharmaceutical companies offer discount cards or coupons that reduce co-pays for targeted therapies. Medical News Today recommends checking if any are available for your treatment.

9. Advocate for Value-Based Pricing and Biosimilar Uptake 📉

Support policies that encourage the use of biosimilars and value-based pricing. Discuss these options with your healthcare provider, as they can help lower costs over time.

10. Stay Informed and Communicate Openly 📲

Stay up-to-date on new generics, biosimilars, and patient support programs. Maintain open communication with your healthcare team about financial concerns, as they may be able to identify cost-saving options tailored to your specific situation.

11. Monitor Bookimed for Updates and New Articles 📚

You can also stay informed by checking for new articles related to targeted therapy, JCI-certified clinics, and treatment options on Bookimed.com. A Bookimed coordinatoris always available to assist you, provide personalized guidance, and answer any questions you may have, completely free for patients.

By following these tips, you can reduce the financial burden of targeted therapy while ensuring you get the most effective treatment.

Now, let’s take a look at success stories and patient reviews to see how targeted therapy has made a real difference in the lives of cancer patients. ▶️

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Success Stories And Patient Reviews

Real experiences help patients understand what to expect. In this section, we share first-hand stories from people who have undergone targeted therapy abroad. Their reviews reflect not just outcomes, but also how they felt during treatment, how clinics supported them, and what helped them make informed decisions. You’ll find both written and video testimonials here:

Targeted Therapy Success Stories

This positive experience with Bookimed showcases how effective communication and professional support can make a significant difference in the treatment journey. Similarly, another patient shares their story of finding new options and the ease of working with the team to arrange treatment at Memorial Şişli Hospital. The assistance they received reflects the personalized and reliable service Bookimed offers to patients seeking targeted therapy options.

These success stories highlight the value of having a trusted partner throughout the medical process, especially when exploring advanced treatments. Whether through clear communication or ongoing support, Bookimed helps patients navigate their healthcare journey with confidence and ease. As we continue to see in these reviews, finding the right medical support can truly make all the difference in achieving better outcomes.

FAQs

❓1. What types of cancer can be treated with targeted therapy?

Targeted therapy is most effective for cancers with identifiable genetic mutations or protein markers. Common indications include:

  • Lung cancer (EGFR, ALK, ROS1 mutations);
  • Breast cancer (HER2-positive);
  • Colorectal cancer (KRAS, BRAF mutations);
  • Prostate cancer (PSMA expression);
  • Leukemia and lymphoma;
  • Neuroendocrine tumors.

Before treatment, patients typically undergo genetic or biomarker testing to determine eligibility.

❓2. How is targeted therapy different from chemotherapy?

Targeted therapy acts on specific molecular targets involved in cancer growth, while chemotherapy affects all rapidly dividing cells, both cancerous and healthy. As a result:

  • Targeted therapy is usually less toxic.
  • Side effects are more predictable and manageable.
  • It may be given orally or intravenously, depending on the drug.

However, not all cancers are suitable for targeted therapy.

❓3. What is the average cost of targeted therapy abroad?

Costs vary widely by country, clinic, and drug used. Average starting prices:

  • Turkey: from $2,500;
  • Germany: from $5,900;
  • Thailand: from $3,500;
  • Israel: from $15,000 to $30,000;
  • Italy: €70,000-78,000 over the course of treatment.

Costs may include consultations, drug administration, lab testing, and follow-up. Prices in the U.S. often exceed $170,000–240,000 per year for similar treatments.

❓4. Are there risks or side effects with targeted therapy?

Yes, but they vary by drug. Common side effects may include:

  • Fatigue;
  • Skin rash or dryness;
  • High blood pressure;
  • Diarrhea;
  • Liver function changes.

Unlike chemotherapy, targeted therapies generally don’t cause hair loss or severe nausea. Kidney or liver function should be monitored, especially with radioligand therapy like Lutetium-177.

❓5. Can I access targeted therapy through clinical trials?

Yes. Clinical trials often offer access to new or experimental targeted therapies, sometimes at reduced or no cost. They may cover drug costs, diagnostic tests, and even travel in some cases. You can search for active trials at clinicaltrials.gov or ask your doctor or Bookimed coordinator about available options in your destination country.

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Conclusion

Targeted therapy offers a personalized and effective approach to cancer treatment for eligible patients. Whether you’re comparing costs, countries, or clinic standards, having the right information helps you make confident decisions. The Bookimed medical team is always ready to support you—free of charge—by selecting trusted clinics, explaining treatment options, and organizing care anywhere in the world.

The cost of targeted cancer therapy shows significant variation across different countries. As reported by the Cancer Therapy Advisor, the United States had the highest treatment expenses in 2025, with monthly costs frequently surpassing $27,000.

In contrast, Canadian prices are generally more affordable—ranging between $3,000 and $4,000 per month thanks to provincial health coverage that helps reduce patients' financial burden, according to data from the National Library of Medicine under the National Institutes of Health.

In Australia, treatment costs—initially between $5,000 and $11,000are substantially reduced due to subsidies through the Pharmaceutical Benefits Scheme (PBS), according to the Australian Prescriber.

Germany’s monthly costs are estimated at approximately $5,900 USD.

Meanwhile, Turkey provides targeted therapy for around $2,500 USD per month.

In Thailand, the monthly price ranges from $3,150 to $3,500 USD.

Italy's cost varies more widely, with full treatment expenses estimated between €70,000 and €78,000.

Finally, in Israel, the average cost ranges between $15,000 and $30,000.