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What's the Cost of Amyotrophic lateral sclerosis Diagnosis and Treatment in Republic of Korea?

The average price for Amyotrophic lateral sclerosis diagnostic and treatment in Republic of Korea is $21,000, the minimum price is $21,000, and the maximum price is $21,000.
Republic of KoreaTurkeyAustria
Stem Cell Therapyfrom $730from $7,200from $8,500
Plasmapheresisfrom $4,200from $1,200from $2,000
Stem cell therapy for ALS (amyotrophic lateral sclerosis)-from $30,000from $60,000
Data verified by Bookimed as of July 2026, based on patient requests and official quotes from 103 clinics worldwide. Median costs are based on real invoices (2025–2026) and updated monthly. Actual prices may vary.

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Best Amyotrophic lateral sclerosis Treatment Centers in Republic of Korea: 4 Verified Options and Prices

The Bookimed clinic ranking is based on data science algorithms, providing a trusted, transparent, and objective comparison. It takes into account patient demand, review scores (both positive and negative), the frequency of updates to treatment options and prices, response speed, and clinic certifications.
Severance Hospital
Soon Chun Hyang University Hospital
RE:YOUTH (YONSEI BH Arterial Stemcell Clinic)

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verified

Byung-hee Lee

42 years of experience

Dr. Byung-hee Lee has 42 years of experience of experience and has performed 900+ treatments, specializing in innovative approaches for neurological conditions.

  • Founding member of the Korean Society of Interventional Neurology
  • Founding member of the Korean Stroke Society
  • Author of 24 SCI journal articles
  • Presented at over 50 international and domestic conferences
  • Regular member of the American Stroke Association and World Stroke Society
verified

Kyoung Heo

The doctor is a leading neurologist in South Korea, specializing in epilepsy treatment. Currently, the doctor serves as the Head of the Neurology Department at Yonsei Severance Hospital.

The doctor graduated from Yonsei University College of Medicine and is an active member of several professional organizations, including The Korean Epilepsy Society, The Korean Neurological Association, and The Korea Medical Association.

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Updated: 03/13/2025
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This page may feature information relating to various medical conditions, treatments, and healthcare services available in different countries. Please be advised that the content is provided for informational purposes only and should not be construed as medical advice or guidance. Please consult with your doctor or a qualified medical professional before starting or changing medical treatment.

Expert Overview about Amyotrophic lateral sclerosis Treatment in Republic of Korea

These FAQs come from real patients seeking medical assistance through Bookimed. Answers are given by experienced medical coordinators and trusted clinic representatives.

What unique ALS treatments are available in South Korea that are not found elsewhere?

South Korea offers Neuronata-R, the world first licensed stem cell therapy for ALS. This autologous mesenchymal stem cell treatment is currently only available at specialized Korean university hospitals. It aims to slow disease progression through intrathecal injections into the spinal fluid.

  • Arterial delivery: RE:YOUTH clinic uses arterial methods for 100% direct organ targeting during therapy.
  • Integrative medicine: Specialized centers combine Parkinson-level care with bee-venom pharmacopuncture and herbal decoctions.
  • Specialized facilities: Hanyang University Medical Center operates a dedicated clinic focused strictly on ALS.
  • Regional standards: Korean protocols maintain higher tracheostomy rates for improved late-stage respiratory management.

Bookimed Expert Insight: While many countries offer experimental stem cell treatments, South Korea stands out because Neuronata-R is officially licensed for clinical use. Facilities like RE:YOUTH specialize in arterial delivery to ensure cells reach target organs. This regulatory approval provides a level of official oversight rarely found in other global stem cell hubs.

Patient Consensus: Patients note that while Korean clinics offer fast access to new treatments, the logistical effort is high. They suggest prioritizing established hospitals over smaller clinics to ensure comprehensive multidisciplinary support and genuine clinical trials.

Which hospitals in South Korea are most experienced in ALS diagnosis and multidisciplinary management?

South Korean tertiary hospitals provide specialized amyotrophic lateral sclerosis (ALS) care through dedicated clinics and multidisciplinary teams. Leading centers like Hanyang University Hospital and Severance Hospital integrate neurology, rehabilitation, and respiratory support. These institutions also offer innovative treatments including stem cell therapy and plasmapheresis.

  • Hanyang University Hospital: Opened Koreas first dedicated ALS clinic with significant clinical research experience.
  • Severance Hospital: This JCI-accredited facility manages 1.6 million outpatients annually using advanced AI.
  • Asan Medical Center: Offers comprehensive neurological evaluations and participates in global ALS multi-center studies.
  • RE:YOUTH Yonsei BH: Specializes in arterial stem cell therapy to deliver cells directly to organs.

Bookimed Expert Insight: Hospital volume is a key indicator of diagnostic precision in Korea. Severance Hospital manages over 1.6 million outpatients annually. Dr. Yeon Jung Kim at Asan Medical Center brings international experience from New York Presbyterian. These high-volume centers often provide access to government programs that reduce out-of-pocket patient costs.

Patient Consensus: Patients emphasize reaching out to specialized neurology departments at major Seoul centers to confirm multidisciplinary team availability. Many note that connecting with local patient advocacy groups helps navigate the specific care pathways in South Korea.

Will international health insurance cover NeuroNata-R or stem-cell injections in Korea?

International health insurance rarely covers NeuroNata-R or stem cell injections in South Korea. Insurers typically classify these regenerative therapies as experimental or investigational. While South Korea conditionally approved NeuroNata-R for ALS, it lacks full approval from the United States Food and Drug Administration.

  • Experimental status: Insurers deny most claims for regenerative therapies lacking full FDA approval.
  • Local coverage: The South Korean National Health Insurance system does not cover NeuroNata-R.
  • Standard care: Established procedures like bone marrow transplants for blood cancers are usually covered.
  • Clinic documentation: Centers like RE:YOUTH provide documentation to help patients seek possible reimbursement.

Bookimed Expert Insight: Patient volume data suggests many travel to South Korea for arterial stem cell delivery. This method, available at clinics like RE:YOUTH, targets organs directly rather than using traditional IV. Doctors like Dr. Byung-hee Lee focus on this precision, yet patients should still plan for out-of-pocket costs.

Patient Consensus: Patients note that while the medical bureaucracy is complex, having detailed clinical reports in English is vital. They often emphasize that navigating these costs alone is the most stressful part of the journey.

What does Korean palliative-care practice for ALS look like for airway and nutrition support?

Palliative care for ALS in South Korea emphasizes intensive medical interventions within tertiary hospitals. Practices prioritize invasive airway management and procedural nutrition support. Approximately 35% of patients undergo tracheostomy. This rate is significantly higher than in most Western healthcare systems.

  • Tracheostomy usage: Roughly 32.2% of patients utilize ventilators within 24 months of diagnosis.
  • Airway transitions: Respiratory care often moves rapidly from non-invasive masks to invasive surgical methods.
  • Gastrostomy support: About 26.6% of patients receive Percutaneous Endoscopic Gastrostomy (PEG) for nutrition.
  • Multidisciplinary teams: Specialized teams including dietitians and pharmacists manage complex enteral feeding protocols.

Bookimed Expert Insight: Clinical data reveals South Korea serves as a major hub for complex neurology. Severance Hospital alone manages 1.6 million outpatients annually. This high volume supports a massive infrastructure for technical interventions like tracheostomies. However, ALS is not currently eligible for formal hospice benefits under Korean law. Patients often transition to high-capacity centers like Gachon University Gil Medical Center for advanced support.

Patient Consensus: Patients note that family members often lead daily care for feeding tubes after discharge. Most local discussions regarding long-term management occur on Korean-language medical forums rather than international platforms.

How long does a typical evaluation/treatment cycle last for an international ALS patient in Korea?

Standard evaluations for ALS in South Korea typically require 1 week. Treatment cycles vary by protocol, with single stem cell therapy cycles lasting 9 to 10 days. Advanced protocols or drug infusions like Edaravone often require stays of 10 to 14 days per session.

  • Diagnostic evaluation: Standard workups including EMG, NCV, and MRI take approximately 1 week.
  • Stem cell cycle: One cycle of autologous stem cell therapy typically takes 9 to 10 days.
  • Infusion cycles: Edaravone treatment cycles generally require 10 to 14 days of supervised infusions.
  • Extended protocols: Patients receiving multiple injections may stay 4 to 12 weeks or return later.

Bookimed Expert Insight: While major centers like Severance Hospital manage massive patient volumes, specialized clinics focus on specific delivery methods. RE:YOUTH Clinic uses a targeted arterial injection method for stem cell therapy. This emphasizes that treatment time is not just about the drug used. It depends on the complexity of the delivery technology available at the clinic.

Patient Consensus: Patients note it is helpful that major centers have dedicated international teams. These coordinators help speed up the process so evaluations start immediately upon arrival.

Is there after-care or remote follow-up once I return home?

South Korean hospitals provide comprehensive remote follow-up for ALS patients using advanced telemedicine and electronic health record systems. Facilities like Severance Hospital utilize digital imaging and smart building technology to monitor recovery. Patients receive detailed bilingual documentation and instructions to ensure seamless care continuity with local physicians.

  • Telemedicine integration: Severance Hospital uses artificial intelligence and telemedicine for efficient remote patient consultations.
  • Digital monitoring: Electronic health records (EHRs) allow doctors to track patient progress from abroad.
  • Care continuity: Clinics provide bilingual reports to ensure local neurologists can manage ongoing care.
  • Follow-up coordination: International services at specialized centers manage scheduling for virtual check-ins and refills.

Bookimed Expert Insight: While many facilities offer standard follow-up, choosing a clinic with integrated EHRs and AI like Severance Hospital is a game-changer. Their massive volume of 1.6 million outpatients yearly helps them refine remote monitoring protocols. This digital infrastructure ensures your home-country doctor receives precise data, preventing any gaps in your ALS management plan.

What stem cell therapies are available for Amyotrophic lateral sclerosis (ALS) in the Republic of Korea?

South Korea offers Neuronata-R. This autologous bone marrow-derived stem cell therapy has conditional approval for ALS. Specialists also perform arterial stem cell therapy and direct infusion. Major centres like Severance Hospital and RE:YOUTH facilitate these treatments. They use JCI-accredited or Newsweek-ranked facilities across Seoul and Incheon.

  • Neuronata-R therapy: Uses the patient's own bone marrow cells for neuroprotection via intrathecal injection.
  • Arterial infusion: RE:YOUTH clinic provides direct arterial stem cell delivery for neurological support.
  • Certified expertise: Dr Byung-hee Lee specialises in interventional neurology and stem cell applications.
  • Multi-stage diagnostics: Specialists like Dr Yeon Jung Kim conduct neurological evaluations before treatment.

Bookimed Expert Insight: Neuronata-R is the standard approved therapy. RE:YOUTH clinic distinguishes itself by limiting intake to two patients daily. This high-focus model lets Dr Byung-hee Lee customise arterial infusion protocols. This approach is rare, even in a major hub like Seoul. It typically suits patients seeking intensive, individualised interventional care.

Are there ALS treatments available in the Republic of Korea that are not yet approved in Australia or other Western countries?

South Korea offers Neuronata-R, a stem cell therapy for amyotrophic lateral sclerosis not yet approved in Australia. This treatment uses autologous bone marrow-derived mesenchymal stem cells. The Ministry of Food and Drug Safety granted it conditional approval in 2013 to slow disease progression.

  • Unique delivery: RE:YOUTH clinic uses direct arterial infusion to deliver stem cells to the brain.
  • Clinical status: Neuronata-R is administered via intrathecal injection into the spinal canal for patients.
  • Institutional expertise: JCI-accredited Severance Hospital serves over 4,000,000 patients annually across multidisciplinary units.
  • Global recognition: Gachon University Gil Medical Center ranks among the World's Best Hospitals by Newsweek.

Bookimed Expert Insight: While most international centres use spinal injections, specific Korean clinics like RE:YOUTH specialise in arterial stem cell delivery. This method aims for more direct targeting of neurological tissue. Dr Byung-hee Lee at this clinic is a founding member of the Korean Society of Interventional Neurology. He brings rare vascular expertise to ALS care.

Patient Consensus: Patients note South Korea provides rapid access to clinical trial options and regenerative therapies. They recommend getting written English summaries of all procedures. These summaries help Australian neurologists manage follow-up care.

Which hospitals in the Republic of Korea specialise in multidisciplinary care for ALS patients?

Major South Korean tertiary hospitals provide ALS care through integrated neurology and rehabilitation teams. Facilities like Severance Hospital and Hanyang University Hospital specialise in combined therapy models. These centres coordinate neurologists, pulmonologists, and physiotherapists to manage motor neuron symptoms. This approach aims to improve quality of life.

  • Severance Hospital: This JCI-accredited Seoul facility serves 4,000,000 outpatients annually with dedicated rehabilitation centres.
  • Hanyang University Hospital: It operates Korea's first specialised ALS clinic focusing on integrated clinical research.
  • Asan Medical Center: Specialists like Dr Yeon Jung Kim provide neurological evaluations and cognitive care.
  • Gachon University Gil Medical Center: A Newsweek-ranked multidisciplinary hospital located 1 hour from Incheon International Airport.
  • RE:YOUTH Clinic: Dr Byung-hee Lee offers arterial stem cell therapy for chronic neurological conditions.

Bookimed Expert Insight: Large university hospitals like Severance manage massive patient volumes. In contrast, smaller specialised clinics such as RE:YOUTH restrict intake to 2 patients daily. This allowing patients to choose between high-capacity research environments and high-attention VIP settings.

How does the approach to respiratory care for ALS patients in the Republic of Korea compare to standard practices?

Korean ALS centres prioritise long-term survival through invasive ventilation more frequently than Western clinics. While standards often focus on palliative care, specialists here frequently use tracheostomies. This approach extends life significantly for patients facing respiratory failure within JCI-accredited facilities like Severance Hospital.

  • Tracheostomy rates: Approximately 33% of Korean patients select invasive ventilation in later stages.
  • Survival focus: Medical practices emphasise long-term mechanical ventilation over withdrawing support during palliative care.
  • Integrative management: Centres combine modern BiPAP systems with traditional Korean medicine like acupuncture.
  • Multidisciplinary units: Major hospitals like Gachon University Gil Medical Center integrate neurologists and respiratory specialists.

Bookimed Expert Insight: South Korea leads in combining conventional neurology with regenerative techniques. Major centres like Severance Hospital hold JCI and KOIHA accreditations. Meanwhile, smaller specialised clinics like RE:YOUTH offer unique arterial stem cell infusions. This medical landscape allows patients to access both intensive respiratory support and experimental therapies. These options are often unavailable in other regions.

Patient Consensus: Patients note it is important to start non-invasive ventilation early for better quality of life. In Korea, families should clarify emergency contact pathways. They should also ask how doctors explain the transition to long-term ventilation.

Are there opportunities for international patients to participate in clinical trials for ALS in the Republic of Korea?

International patients can access amyotrophic lateral sclerosis (ALS) research and specialised therapies in South Korea. Facilities like Severance Hospital and Gachon University Gil Medical Center participate in global studies. Research initiatives like the Pan-Asian Consortium for Treatment and Research in ALS (PACTALS) facilitate regional trial access.

  • Clinical collaboration: PACTALS connects researchers at institutions such as Hanyang University Hospital.
  • Regenerative medicine: Specialised clinics like RE:YOUTH offer arterial stem cell therapy for chronic diseases.
  • Standard of care: Major Seoul hospitals hold Joint Commission International (JCI) accreditation for safety.
  • Trial eligibility: Participation typically requires strict screening and on-site follow-up at the sponsoring centre.

Bookimed Expert Insight: South Korea is a top-tier destination for neurological care. It ranks 6th globally by patient requests. Large hospitals like Severance manage 4,000,000 patients annually. In contrast, smaller VIP clinics such as RE:YOUTH limit intake to two patients daily. This allow patients to choose between high-volume research centres or personalised regenerative therapy environments.

Patient Consensus: Patients note that private treatment is accessible. However, joining a trial requires careful planning for repeated international travel. Long-term trials often have strict residency-based eligibility rules. Logistics like visa requirements and mobility support must be confirmed with the investigator before travelling to South Korea.

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