The total cost of melanoma treatment in Spain varies based on the specific treatment plan. A consultation with a specialist is approximately $650. An ultrasound of lymph nodes costs around $300. Blood tests range from $150 to $300, while a PET-CT scan is estimated between $1,650 and $2,200. A biopsy of lymph nodes, if necessary, costs $700, and histological analysis is about $400. Chemotherapy or immunotherapy is approximately $3,850 to $6,050, and radiation therapy ranges from $17,500 to $19,700. The treatment program is determined after an individual assessment by a medical professional.