CAR T-cell Therapy in Israel: 21-Night All-Inclusive Package with Price
What's included in this package
Medical Procedures
- CAR T-cell therapy
- 3 meals per day by nutritionist
- 24-hr nurse services
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Biochemistry blood test
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
Duration
- 21 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
Sheba Pediatric CAR-T Program for Non-Hodgkin Lymphomas (DLBCL, FL, MCL)
At Sheba Medical Center, children and young patients with Non-Hodgkin lymphomas have access to one of the most advanced and trusted CAR-T therapy programs in the world. The program focuses on treating diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL), especially in relapsed or treatment-resistant cases using highly personalized immunotherapy.
A Personalized Treatment Designed for Each Child
CAR-T therapy uses the patient’s own immune system to identify and destroy cancer cells. This approach offers new hope for children and young patients when standard therapies are no longer effective.
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:
Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target lymphoma
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body over time and offering the potential for long-term remission.
Expert Pediatric Leadership and Care
The pediatric CAR-T program is led by Prof. Amos Toren, one of the most experienced specialists in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.
The program includes:
Dedicated pediatric CAR-T units with 24/7 expert monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and pediatric specialists
A supportive, family-centered environment designed for children
Full international patient support, including travel and care coordination
Proven Outcomes and Global Expertise
Sheba is a global leader in pediatric CAR-T therapy, with strong clinical outcomes:
~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults
The program is highly experienced in treating complex and high-risk lymphoma cases, offering advanced options when other treatments have been exhausted.
Comprehensive Evaluation and Support
Each child undergoes a thorough diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, ensuring families feel supported and informed at every stage.
A Trusted Place for Advanced Pediatric Cancer Care
By combining cutting-edge science, rapid access to treatment, and compassionate pediatric care, Sheba provides one of the most trusted environments for treating Non-Hodgkin lymphomas with CAR-T therapy focused on achieving remission and helping children return to a healthy, active life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Amos Toren is a pediatric hemato-oncologist at Sheba Medical Center. He served as Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division. Dr. Toren holds a PhD in Human Genetics. He specializes in CAR T-cell therapy and bone marrow transplantation for children. Forbes Israel has recognized his expertise in hematology.
- Served as the Head of the Hematology Division at Tel Aviv University.
- Treats complex cases of leukemia, lymphoma, and rare pediatric cancers.
- Member of the American Society of Hematology and European Group for Blood and Marrow Transplantation.
- Collaborates on research with the NIH and St. Jude Children’s Research Hospital.
How are we doing?
About the clinic
CAR T-cell therapy at Sheba Medical Center in Ramat Gan, Israel, is a specialized immunotherapy for blood cancers and autoimmune diseases. The medical center is ranked #7 worldwide by Newsweek 2026 and holds JCI accreditation. Laboratory preparation for the treatment is around $20,000, and regular department hospitalization may cost around $31,500.
Advanced Cell Therapy Program
Sheba Medical Center operates one of the largest programs in the region. The hospital has treated 500+ patients, including over 100 children. The program treats conditions like leukemia, lymphoma, and multiple myeloma. Remission rates for pediatric leukemia are around 80%. For aggressive lymphomas, response rates often exceed 50%. The center also conducts research for autoimmune diseases like lupus and scleroderma.
Fast On-Site Manufacturing
The hospital uses its own Advanced Biotherapy Center to create the treatment. This facility follows Good Manufacturing Practice (GMP) standards. Creating the modified cells on-site shortens the time from cell collection to infusion. The process takes about 10–11 days, which is much faster than sending cells to external labs. Prof. Dr. Arnon Nagler, a pioneer in the field, notes that in-house manufacturing helps maintain high cell quality.
Treatment Process and Costs
The treatment follows a specific protocol to prepare the body and monitor recovery. The process includes several stages and related costs:
- Apheresis: Collecting T-cells from the patient's blood costs around $6,600.
- Specialized Testing: Lab tests for genetic mapping and malignancy markers are around $6,000.
- Hospitalization: A stay of up to 21 days for monitoring is around $31,500.
- Total Deposit: The hospital requires a deposit of around $60,000 before arrival.
Recovery and Monitoring
Patients stay in the hospital for at least two weeks after the infusion. Dedicated units provide 24/7 monitoring and access to ICU support if needed. The full recovery period usually takes about two to three months. The team at the Hemato-Oncology Center is led by Prof. Dr. Arnon Nagler, who serves as the center's President.
To learn more about participating in the CAR T-cell research program, you can leave a request on Bookimed.
Payment & Rewards
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You make your payment directly at the clinic or to their official bank account.
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