Sheba Pediatric CAR-T Program for Multiple Myeloma at JCI accredited and Top-10 Hospitals 2026 by Newsweek Hospital
What's included in this package
Medical Procedures
- CAR T-cell therapy
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Complete blood count (CBC)
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
- Complete blood count with cancer markers and a proteinogram
Duration
- 21 days in the hospital
Accommodation
Accommodation is not included
Transport
Transfer airport-clinic-airport
Additional information
Sheba Pediatric CAR-T Program for Multiple Myeloma
At Sheba Medical Center, children and young patients with multiple myeloma have access to one of the most advanced and trusted CAR-T therapy programs in the world. While multiple myeloma is more common in adults, Sheba provides highly specialized care for young and complex cases, including relapsed or treatment-resistant disease.
A Personalized Treatment Designed for Each Patient
CAR-T therapy uses the patient’s own immune system to recognize and destroy cancer cells. For patients with multiple myeloma, this innovative approach offers a highly targeted option when standard treatments are no longer effective.
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:
Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target myeloma cells
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body and offering the potential for long-term disease control and remission.
Expert Pediatric Leadership and Care
The program is led by Prof. Amos Toren, a globally recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.
Patients are treated within a highly specialized environment that includes:
Dedicated pediatric and young adult CAR-T units with 24/7 monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and supportive care specialists
A patient- and family-centered approach, ensuring comfort and continuous support
Full international patient services, including travel and care coordination
Advanced Expertise in Complex Cases
Sheba is a global leader in CAR-T therapy, with strong clinical outcomes across hematologic cancers:
~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults
The program is experienced in managing rare, complex, and high-risk myeloma cases, offering advanced treatment options when other therapies have been exhausted.
Comprehensive Evaluation and Ongoing Support
Each patient undergoes a detailed diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, ensuring clear communication and a supportive experience for international families.
A Trusted Place for Advanced Care
By combining cutting-edge science, rapid access to therapy, and compassionate care, Sheba offers one of the most advanced CAR-T programs for multiple myeloma focused on improving outcomes and helping patients return to a better quality of life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Amos Toren is a pediatric hemato-oncologist at Sheba Medical Center. He served as Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division. Dr. Toren holds a PhD in Human Genetics. He specializes in CAR T-cell therapy and bone marrow transplantation for children. Forbes Israel has recognized his expertise in hematology.
- Served as the Head of the Hematology Division at Tel Aviv University.
- Treats complex cases of leukemia, lymphoma, and rare pediatric cancers.
- Member of the American Society of Hematology and European Group for Blood and Marrow Transplantation.
- Collaborates on research with the NIH and St. Jude Children’s Research Hospital.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and ranked 7th worldwide by Newsweek in 2026. It treats over 2 million patients annually and is a global leader in CAR-T and TIL immunotherapies. Core specialties include oncology, immunotherapy, precision medicine, and cardiology.
- JCI and ISO accredited with eight consecutive years in the Newsweek global Top 10.
- In-house CAR-T manufacturing through its GMP-certified Advanced Biotherapy Center (ABC).
- Over 200 Sheba doctors are listed among Forbes' Top Doctors.
- One of the few centers worldwide developing CAR-T therapies for severe autoimmune diseases.
- Campus includes six major hospitals, among them the Leviev Heart Center and Edmond and Lily Safra Children's Hospital.
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