CAR T-cell Therapy in Israel: 21-Night All-Inclusive Package with Price
What's included in this package
Medical Procedures
- CAR T-cell therapy
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Complete blood count (CBC)
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
- Complete blood count with cancer markers and a proteinogram
Duration
- 21 days in the hospital
Accommodation
Accommodation is not included
Transport
Transfer airport-clinic-airport
Additional information
Sheba Pediatric CAR-T Program for Multiple Myeloma
At Sheba Medical Center, children and young patients with multiple myeloma have access to one of the most advanced and trusted CAR-T therapy programs in the world. While multiple myeloma is more common in adults, Sheba provides highly specialized care for young and complex cases, including relapsed or treatment-resistant disease.
A Personalized Treatment Designed for Each Patient
CAR-T therapy uses the patient’s own immune system to recognize and destroy cancer cells. For patients with multiple myeloma, this innovative approach offers a highly targeted option when standard treatments are no longer effective.
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:
Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target myeloma cells
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body and offering the potential for long-term disease control and remission.
Expert Pediatric Leadership and Care
The program is led by Prof. Amos Toren, a globally recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.
Patients are treated within a highly specialized environment that includes:
Dedicated pediatric and young adult CAR-T units with 24/7 monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and supportive care specialists
A patient- and family-centered approach, ensuring comfort and continuous support
Full international patient services, including travel and care coordination
Advanced Expertise in Complex Cases
Sheba is a global leader in CAR-T therapy, with strong clinical outcomes across hematologic cancers
The program is experienced in managing rare, complex, and high-risk myeloma cases, offering advanced treatment options when other therapies have been exhausted.
Comprehensive Evaluation and Ongoing Support
Each patient undergoes a detailed diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, ensuring clear communication and a supportive experience for international families.
A Trusted Place for Advanced Care
By combining cutting-edge science, rapid access to therapy, and compassionate care, Sheba offers one of the most advanced CAR-T programs for multiple myeloma focused on improving outcomes and helping patients return to a better quality of life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Amos Toren is a pediatric hemato-oncologist at Sheba Medical Center. He served as Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division. Dr. Toren holds a PhD in Human Genetics. He specializes in CAR T-cell therapy and bone marrow transplantation for children. Forbes Israel has recognized his expertise in hematology.
- Served as the Head of the Hematology Division at Tel Aviv University.
- Treats complex cases of leukemia, lymphoma, and rare pediatric cancers.
- Member of the American Society of Hematology and European Group for Blood and Marrow Transplantation.
- Collaborates on research with the NIH and St. Jude Children’s Research Hospital.
How are we doing?
About the clinic
CAR T-cell therapy at Sheba Medical Center in Ramat Gan, Israel, is a specialized immunotherapy for blood cancers and autoimmune diseases. The medical center is ranked #7 worldwide by Newsweek 2026 and holds JCI accreditation. Laboratory preparation for the treatment is around $20,000, and regular department hospitalization may cost around $31,500.
Advanced Cell Therapy Program
Sheba Medical Center operates one of the largest programs in the region. The hospital has treated 500+ patients, including over 100 children. The program treats conditions like leukemia, lymphoma, and multiple myeloma. Remission rates for pediatric leukemia are around 80%. For aggressive lymphomas, response rates often exceed 50%. The center also conducts research for autoimmune diseases like lupus and scleroderma.
Fast On-Site Manufacturing
The hospital uses its own Advanced Biotherapy Center to create the treatment. This facility follows Good Manufacturing Practice (GMP) standards. Creating the modified cells on-site shortens the time from cell collection to infusion. The process takes about 10–11 days, which is much faster than sending cells to external labs. Prof. Dr. Arnon Nagler, a pioneer in the field, notes that in-house manufacturing helps maintain high cell quality.
Treatment Process and Costs
The treatment follows a specific protocol to prepare the body and monitor recovery. The process includes several stages and related costs:
- Apheresis: Collecting T-cells from the patient's blood costs around $6,600.
- Specialized Testing: Lab tests for genetic mapping and malignancy markers are around $6,000.
- Hospitalization: A stay of up to 21 days for monitoring is around $31,500.
- Total Deposit: The hospital requires a deposit of around $60,000 before arrival.
Recovery and Monitoring
Patients stay in the hospital for at least two weeks after the infusion. Dedicated units provide 24/7 monitoring and access to ICU support if needed. The full recovery period usually takes about two to three months. The team at the Hemato-Oncology Center is led by Prof. Dr. Arnon Nagler, who serves as the center's President.
To learn more about participating in the CAR T-cell research program, you can leave a request on Bookimed.
Payment & Rewards
You don’t pay for our services
You make your payment directly at the clinic or to their official bank account.
Some clinics may require a deposit as a part of their policy.
Spread out your payments with installment options.
Earn rewards for referring friends to Bookimed.