Sourasky Medical Center (Ichilov)
Sourasky Medical Center (Ichilov)
Israel, Tel Aviv
Ari Raphael
29 years of experience
accreditations :
Clinic is certified :
Why choose Israel for immunotherapy for breast cancer?
Access advanced Immunotherapy for breast cancer solutions in trusted clinics from $28,000.
| Israel | Turkey | Austria | |
| Immunotherapy for breast cancer | ≈ $28,000 | from $8,000 | ≈ $18,000 |
Day 1 - Arrival
Day 2 - Pre-Operation
Day 3 - Immunotherapy
Day 4 - Post-Operation
Week 1 to Week 3 - Rehabilitation
Week 4 to Week 6 - Rehabilitation
Please note that each patient reacts differently to immunotherapy. Therefore, this guide might not perfectly correspond to your individual journey. Always consult with your medical team for personalized information.
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Dr. Ari Raphael leads the TASMC oncology project of PSIFAS, Israel's National Genomic Medicine Initiative, focusing on immunotherapy for breast cancer.
Prof. Merimsky leads the Soft Tissue and Bone Oncology Unit at Sourasky Medical Center, with decades of expertise in sarcoma and breast cancer treatments.
Specialist with dedicated expertise in oncological gynecology and radiotherapy at Sourasky Medical Center.
Director of oncology hospitalization at Tel Aviv Medical Center – Dr. Stepfansky leads immunotherapy research and treatment.
Immunotherapy for breast cancer in Israel is a sophisticated, integrated standard for aggressive subtypes like triple-negative and HER2-positive cases. Israeli oncologists utilize advanced PD-1/PD-L1 inhibitors and targeted biological therapies inside Joint Commission International-accredited facilities to achieve oncology success rates approaching 90%.
Bookimed Expert Insight: Israeli oncology centers like Sourasky Medical Center treat 40,000 cancer patients annually. This massive volume allows their Molecular Tumor Boards to refine personalized protocols faster than smaller regional clinics. If you have triple-negative breast cancer, look for the KeyNote 522 protocol, which is a specialized specialty here.
Patient Consensus: Patients value how centers simplify complex data while providing practical support like interpreters. Many feel more secure knowing their treatment follows the global gold standard for Stage 2-3 aggressive cancers.
Triple-negative breast cancer (TNBC) responds best to immunotherapy, particularly when tumors express the PD-L1 protein. This subtype is highly immunogenic, making it susceptible to checkpoint inhibitors like Pembrolizumab (Keytruda) when used alongside chemotherapy for high-risk early-stage or metastatic conditions.
Bookimed Expert Insight: Israeli oncology centers like Sourasky Medical Center utilize Foundation One CDx genetic testing to identify rare immunotherapy biomarkers. While global averages for immunotherapy range from $3,500, Israel offers these advanced protocols at approximately 46% less than US costs.
Patient Consensus: Many patients find immunotherapy side effects more manageable than traditional chemotherapy. Those with high PD-L1 expression often report reaching complete remission through personalized Israeli treatment protocols.
Common immunotherapy drugs for breast cancer in Israel include Pembrolizumab (Keytruda), Trodelvy, and Enhertu. Oncologists focus on checkpoint inhibitors like Keytruda for triple-negative breast cancer. Leading JCI-accredited centers such as Sourasky Medical Center utilize genomic profiling to select targeted biological therapies for metastatic cases.
Bookimed Expert Insight: Israeli oncology centers like Sourasky Medical Center serve 40,000 cancer patients annually. This high volume allows doctors like Dr. Ari Raphael to lead national genomic initiatives. This expertise translates into precise immunotherapy efficacy tracking that significantly improves survival rates for aggressive triple-negative tumors.
Patient Consensus: Patients value how coordinators help navigate complex clinical trial options. Many emphasize that confirming HER2 status early is vital for accessing the right drug protocols.
Immunotherapy is primarily administered via intravenous infusion or subcutaneous injections to stimulate the body's immune response against cancer. Common side effects include manageable fatigue, skin rashes, and flu-like symptoms, though immune-related inflammation of organs like the liver or lungs requires careful monitoring.
Bookimed Expert Insight: While many assume immunotherapy is always a standalone treatment, Israeli protocols like KeyNote 522 frequently combine drugs like Keytruda with chemotherapy for triple-negative breast cancer. This strategic pairing significantly improves response rates but requires tighter coordination of bloodwork to manage overlapping side effects.
Patient Consensus: Patients report that while fatigue occurs after infusions, it feels significantly less draining and shorter than traditional chemotherapy. Most suggest preparing for minor skin changes like dryness or rosacea, which are easily managed with topical creams.
Israel actively hosts Phase 1 through 3 clinical trials for breast cancer immunotherapy at centers like Sourasky Medical Center and Hadassah Medical Center. Research focuses on triple-negative breast cancer, utilizing checkpoint inhibitors, specialized cancer vaccines, and advanced cellular therapies like tumor-infiltrating lymphocytes to improve outcomes.
Bookimed Expert Insight: While many global trials focus solely on drugs, Israeli research centers uniquely integrate computational biology. Experts like Dr. Ari Raphael at Sourasky Medical Center lead phase 1 trials combining T-Cell sequencing with immunotherapy. This high-tech approach helps identify which patients will respond best to specific biological treatments before they start.
Patient Consensus: Patients value the speed of enrollment and the supportive coordination found in Israeli oncology departments. Many emphasize the importance of having a dedicated coordinator to navigate complex trial protocols and logistical hurdles during treatment.
Accessing immunotherapy for breast cancer in Israel requires advanced molecular profiling to confirm tumor suitability for checkpoint inhibitors like Keytruda (pembrolizumab). Patients must undergo PD-L1 testing or genomic sequencing at JCI-accredited centers such as Sourasky Medical Center or Hadassah Medical Center to qualify for personalized protocols.
Bookimed Expert Insight: While drug costs range from $3,500, the real value in Israel is the diagnostic speed. Centers like Sourasky serve 40,000 cancer patients yearly, maintaining a 90% oncology success rate. Their high patient volume allows faster enrollment into next-generation clinical trials compared to smaller European facilities.
Patient Consensus: Success depends on confirming cancer subtypes like triple-negative breast cancer early. Patients emphasize having a dedicated coordinator to navigate administrative permits and monitor persistent side effects like thyroid changes.
Israel is a premier neurosurgery hub due to its fusion of high-density medical innovation and elite surgical expertise. Top facilities like Sheba Medical Center integrate AI-guided navigation and real-time intraoperative MRI. Specialized centers report 98% success rates for complex procedures including awake craniotomy and movement disorder treatments.
Bookimed Expert Insight: Data shows a clear divide between public and private options in Israel. Private centers like Assuta Medical Center perform over 92,000 operations annually and allow patients to select their specific lead surgeon. This is a vital advantage for complex cases where a specific expert like Dr. Eli Ashkenazi is preferred for his 1,000+ spine surgery record.
Patient Consensus: Patients emphasize bringing original imaging on a USB for local review to streamline the surgical plan. They also note that private packages often include hotel coordination and airport transfers, making the logistics much smoother.
Israeli neurosurgeons treat a full spectrum of conditions ranging from brain and spinal tumors to complex functional disorders. Specialized centers utilize advanced technologies like Gamma Knife, deep brain stimulation, and intraoperative MRI to manage epilepsy, Parkinson disease, and cerebrovascular pathologies with high precision.
Bookimed Expert Insight: Israeli hospitals often combine specialties to handle complex cases. At Sourasky Medical Center, neurosurgeons like Dr. Zvi Lidar bridge neurosurgery and orthopedics for spinal care. This multidisciplinary approach allows clinics to perform 34,000+ operations annually. Choosing a facility with this crossover expertise often leads to more comprehensive treatment plans for degenerative diseases.
Patient Consensus: Patients value the ability to access specialized treatments like fluorescence-guided surgery for tumors which are often unavailable elsewhere. Many note that the staff is fluent in English and provides clear communication through teleconsultations before traveling.
Israel is home to world-renowned neurosurgery centers like Sourasky Medical Center, Sheba Medical Center, and Hadassah Medical Center. These facilities are globally ranked for treating complex brain tumors, spinal disorders, and movement diseases. They utilize advanced technologies like Gamma Knife, robotic systems, and intra-operative MRI.
Bookimed Expert Insight: Our data shows that while most patients focus on Tel Aviv, Rambam Medical Center in Haifa offers unique expertise in neuro-trauma. It operates a specialized neuro-ICU and serves nearly 1 million patients annually. This makes it an essential choice for complex post-trauma brain surgeries that requires intensive recovery support.
Patient Consensus: Patients note it is important to start consultations early. They often highlight that the precision and follow-up care for complex brain tumors exceeded their expectations. One patient emphasized how quickly they could connect with top professors for second opinions during critical neurosurgical cases.
Israel's leading neurosurgeons include Prof. Zvi Ram, Prof. Shlomi Constantini, and Prof. Itzhak Fried at Sourasky Medical Center. These specialists hold leadership roles in the European Association of Neurosurgical Societies (EANS) and the World Society for Stereotactic and Functional Neurosurgery (WSSFN). They utilize advanced intraoperative mapping and robotic systems.
Bookimed Expert Insight: Data from Sourasky and Sheba indicates a strong correlation between high surgical volumes and patient safety. For example, Sourasky performs 34,000+ operations annually with a 90% oncology success rate. Patients seeking complex tumor removals should prioritize centers like these where surgeons perform hundreds of specific cases each year.
Patient Consensus: Patients emphasize the importance of finding a surgeon who specializes specifically in your condition rather than a generalist. Many note that high-volume centers provide better access to English-speaking staff and coordinated care for international visitors.
International neurosurgery patients in Israel must provide comprehensive medical records including recent MRI or CT scans translated into English. Admission requires a clinical review by specialists to confirm treatment feasibility. Hospitals often mandate full advance payment or a significant deposit before confirming surgery dates or issuing visa support letters.
Bookimed Expert Insight: Data shows that top Israeli facilities like Sheba Medical Center and Hadassah Medical Center handle massive patient volumes, exceeding 1,000,000 people annually. This high demand means clinics prioritize complex or rare cases over routine procedures. Patients with unique or high-risk conditions often receive faster admission approval than those seeking standard treatments available elsewhere.
Patient Consensus: Patients note that having all imaging results ready in English is essential for quick scheduling. Many emphasize that while the medical care is excellent, coordinating around Shabbat closures is necessary to avoid unexpected diagnostic delays.
A standard stay for neurosurgery in Israel ranges from 10 to 14 days for uncomplicated cases. Patients undergoing complex procedures like brain tumor removal or deep brain stimulation often require 4 to 6 weeks. This timeline covers pre-operative diagnostics, the surgical procedure, and essential post-operative monitoring.
Bookimed Expert Insight: Data from Sourasky Medical Center shows they treat over 400,000 patients annually with high success rates. Clinics with such high volumes, like Hadassah or Assuta, often have streamlined discharge protocols. This helps international patients transition to hotel-based recovery faster while maintaining access to top specialists.
Patient Consensus: Patients note it is vital not to rush home too early. Some travelers extended their stay to 3 weeks due to swelling or to ensure they received final surgeon clearance before flying.
Israeli neurosurgery uses robotic guidance, real-time 3D imaging, and incisionless technologies to minimize physical trauma. Systems like Mazor Robotics provide sub-millimeter precision for spine implants. MRI-guided focused ultrasound (MRgFUS) treats tremors without incisions. These advanced tools ensure high accuracy and reduce recovery times.
Bookimed Expert Insight: Israeli clinics like Sourasky or Hadassah integrate proprietary Israeli-born technologies like Surgical Theater before they hit global markets. Our data shows these centers often use VR flight-through models for pre-surgical planning. This allows surgeons to rehearse complex cases, which is a key factor in their 90% success rates.
Patient Consensus: Patients note that technologies like the Gamma Knife allowed them to return home in days rather than weeks. Many move from traditional 10cm incisions to cuts under 2cm when using robotic-assisted systems.
Israel is a global leader in neurosurgery due to its integration of proprietary medical innovations and internationally trained specialists. High-capacity centers like Sourasky Medical Center (Ichilov) perform over 34,000 annual surgeries. Patients access advanced techniques like awake craniotomy and MR-guided focused ultrasound.
Bookimed Expert Insight: Israeli neurosurgery stands out because of the high concentration of dually certified experts. Many top surgeons, such as Dr. Zvi Lidar, are certified to practice in both Israel and the USA. This ensures that patients receive American-standard surgical care while staying in Tel Aviv or Jerusalem. Our data shows that private centers like Assuta offer significantly faster access to these specific specialists compared to the public system.
Patient Consensus: Patients note it is important to confirm a surgeon's specific volume of cases for your exact condition. They also value the ability to get expert second opinions quickly through online consultations with world-renowned professors.
Sheba Medical Center and Sourasky Medical Center (Ichilov) are among the best neurosurgery hospitals in Israel. These JCI-accredited facilities perform thousands of operations annually. They utilize advanced technologies like CyberKnife and intraoperative MRI to treat complex brain tumors and cerebrovascular lesions.
Bookimed Expert Insight: Our data shows that top Israeli centers like Sourasky and Hadassah perform over 40,000 total operations yearly. This high volume allows surgeons to maintain a 90% success rate even in complex oncology cases. Patients seeking robotic spine surgery or deep brain stimulation should focus on these high-capacity municipal centers for the most experienced teams.
Patient Consensus: Patients appreciate that some hospitals quickly coordinate consultations even during regional strikes. Families of pediatric patients especially value surgeons trained at prestigious international institutions.
Israel's leading neurosurgeons include Professor Zvi Ram, Professor Shlomi Constantini, and Professor Itzhak Fried at Sourasky Medical Center. These experts specialize in awake craniotomy, pediatric brain tumors, and functional mapping. Most hold JCI accreditation and international fellowships from institutions like Johns Hopkins and Yale.
Bookimed Expert Insight: Data shows that top-tier Israeli neurosurgeons, such as those at Sourasky Medical Center, often hold dual board certifications in Israel and the US. This unique crossover ensures patients receive American-standard protocols. These specialists typically manage over 34,000 annual operations, providing high-volume clinical experience that smaller private clinics cannot match.
Patient Consensus: Patients note that highly qualified doctors like Professor Shlomo Constantini provide satisfactory answers quickly. People emphasize that outcomes often depend on the hospital’s integrated resources rather than just a doctor's prestige.
Israel is a global leader in neurosurgery, treating complex brain and spinal conditions using robotic-assisted and minimally invasive techniques. Highly specialized units at JCI-accredited centers like Sourasky Medical Center (Ichilov) and Hadassah Medical Center focus on neuro-oncology, pediatric neurosurgery, and functional procedures.
Bookimed Expert Insight: Israeli neurosurgical departments often function as rapid-response hubs for international patients. Data shows that large centers like Sourasky, which serves 1,800,000 patients annually, can organize expert video consultations in a very short time. This speed is critical for neuro-oncology cases where starting treatment a few days earlier significantly impacts outcomes.
Patient Consensus: Patients note that Israeli teams often accept high-risk cases that other hospitals decline. They emphasize the importance of using local coordinators to manage travel logistics or potential local disruptions during their two-week stay.
International patients traveling to Israel for neurosurgery require a valid passport, an entry permit or medical visa, and a formal hospital invitation. You must provide recent MRI or CT scans in DICOM format and detailed medical summaries. Proof of private health insurance and financial stability are also mandatory for border entry.
Bookimed Expert Insight: Our data shows that top neurosurgeons at Hadassah Medical Center and Sourasky often request records 4–6 weeks before arrival. Submitting these early prevents appointment shifts. High-volume centers with over 30,000 annual operations have dedicated portals for secure DICOM file uploads. Using these ensures your surgeon reviews high-quality images before you land in Tel Aviv.
Patient Consensus: Patients emphasize bringing physical copies and digital backups of all scans on a USB drive. They also note that private insurance needs pre-authorization specifically for neurosurgery to avoid payment delays at the clinic.