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How Much Does Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cost in Italy?

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Italy typically costs from $25,000 to $45,000. The final price depends on surgical complexity and hospital stay duration. Patients save around 44% compared to the US, where the average cost is $45,000. Major medical hubs for this treatment include Rome, Bologna, and Milan. Packages often include oncology consultations and intensive care monitoring.

  • Cytoreductive surgery: Complexity of tumor removal significantly impacts the total surgical fee.
  • Hospitalization length: Prolonged stays in the intensive care unit add to the cost.
  • Chemotherapy agents: Specialized heated pharmacological drugs account for about 20% of the price.
  • City variations: Facilities in Milan or Rome may charge 15-20% more than regional centers.

Bookimed Expert Insight: Choosing a specialist with high procedure volumes offers the best value. Dr. Marcello Deraco at Maria Cecilia Hospital has performed over 1,200 CRS and HIPEC procedures. This hospital is JCI-accredited and offers transfers from Bologna International Airport. High-volume centers often manage complex cases more efficiently. This expertise can prevent costly stays from post-operative complications.

Key Benefits

Why choose Italy for hyperthermic intraperitoneal chemotherapy (HIPEC)?

  • Accredited clinics: JCI-certified hospitals provide top-quality care and adhere to international standards.
  • Latest technologies: Italy employs innovative HIPEC methods, including the Performer HT device. This ensures precise temperature control and even drug distribution during treatment.
  • High success rates: HIPEC has demonstrated an efficacy of up to 60% in improving survival rates for patients with peritoneal carcinomatosis.
  • Expert surgeons: Italy boasts leading surgeons, including habilitated professors with over 39 years of experience. They have worked in renowned medical institutions across France, the UK, and the US, performing numerous successful HIPEC procedures.

Access advanced Hyperthermic Intraperitoneal Chemotherapy (HIPEC) solutions in trusted clinics .

ItalyTurkeyAustria
Hyperthermic Intraperitoneal Chemotherapy (HIPEC)from $25,000from $22,500from $40,000
Data verified by Bookimed as of July 2026, based on patient requests and official quotes from 53 clinics worldwide. Median costs are based on real invoices (2025–2026) and updated monthly. Actual prices may vary.

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Transparent Prices & Flexible Installments

No hidden fees – just official clinic prices. Pay at the clinic for Hyperthermic Intraperitoneal Chemotherapy (HIPEC) upon arrival and use a flexible installment plan if needed.

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Bookimed is committed to your safety. We only work with medical institutions that maintain high international standards in Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and have the necessary licenses to serve international patients worldwide.

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Bookimed offers free expert assistance. A personal medical coordinator supports you before, during, and after your treatment, solving any issues. You're never alone on your Hyperthermic Intraperitoneal Chemotherapy (HIPEC) journey.

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  • Supports you at every stage
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Discover the Best Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Clinics in Italy: 2 Verified Options and Prices

The Bookimed clinic ranking is based on data science algorithms, providing a trusted, transparent, and objective comparison. It takes into account patient demand, review scores (both positive and negative), the frequency of updates to treatment options and prices, response speed, and clinic certifications.

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Overview in Italy

Takeaways
Related procedures & Costs
How it works
What to expect
Benefits
Payment
patients recommend -
85%
Surgery Time - 8 hours
Stay in the country - 14 days
Rehabilitation - 30 days
Anesthesia - General anesthesia
Requests processed - 46119
Verified patient reviews - 20
Bookimed fees - $0

Our Doctors

View all Doctors
verified

Marcello Deraco

37 years of experience

Prof. Deraco has successfully treated over 1,200 patients with peritoneal surface malignancies using HIPEC and other advanced techniques at Maria Cecilia Hospital.

  • Director of the Peritoneal Surface Malignancies Unit since 2017
  • Specializes in Cytoreductive Surgery (CRS) and Pressurized Intra-Peritoneal Aerosolized Chemotherapy (PIPAC)
  • Trained at world-renowned institutions including Gustave Roussy Institute and Royal Marsden Hospital
  • Published over 250 scientific articles and 25 book chapters
  • Professor at Milan University, mentoring future surgeons
verified

Luigi Masoni

37 years of experience

Dr. Luigi Masoni is a general surgeon at Ospedale San Carlo di Nancy in Rome. He specializes in oncological surgery and minimally invasive colorectal procedures. Dr. Masoni created a new laparoscopic bilio-intestinal bypass technique. He also developed a three-trocar method for total proctocolectomy.

  • Specialized in colorectal surgery at Thomas Jefferson University Hospital in the USA.
  • Treats pelvic floor disorders and colorectal cancer using minimally invasive techniques.
  • Former lecturer and scientific council member at the University of Rome La Sapienza.
  • Works at a hospital accredited by the Italian National Health Service.

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Reviews about Bookimed: Discover Patients' Insights

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Larisa • Consultation with a mammologist
Italy
Apr 17, 2026
Verified review.
I am now completely confident that I can get the advice I need in my own language at any time!!!!
What I feared most was feeling lost and unheard when I decided to seek a consultation in another country. But that fear vanished as soon as I got in touch with Bookingmed, specifically with Yulia. She looked through my preliminary test results, listened to my concerns and found a suitable clinic quite quickly; then we set a date and that was it! The only inconvenience was that I live near Rome, but the appointment was in Milan – though that wasn’t a problem for me! I was met at the clinic by an interpreter, who was also the coordinator, so I didn’t have to queue or wait around (YAY!!) The doctor answered all my questions patiently and without rushing. Fortunately, my fears turned out to be overblown. The entire process, from my initial enquiry right through to the appointment itself, was well organised. Everything simply worked out. I am now completely confident that I can get the advice I need in my own language at any time!!!! Thank you so much!!!
I was very impressed by how efficient and well-organised the whole process was
As my 'case' was very small, there was nothing to improve – everything was just right!
San Raffaele
Shakiha • Meningioma
Oman
Aug 27, 2021
Verified review.
بصراحة أود شكر الفريق الطبي باكمله في مستشفى سان رفائييل قسم جراحة المخ والاعصاب بقيادة الخبير البروفيسور دكتور مورتيني شكر هو من أعماق قلبي على عدة امور : مستشفى في قمة الدقة والاتقان والتنظيم وفريق طبي متميز اضافة الى ان هذا الدكتور من التواضع والخبرة والاسلوب الراقي لا اجد الكلمات المعبرة لشكره والثناء عليه هو وفريقه المساعد من الجراحين وطبيبة التخدير ووالى اصغر موظف وعامل في هذا المستشفى الانساني واتمنى لهم التوفيق والنجاح في انقاذ ارواح الناس وعلاجهم وشفائهم
About Bookimed service
راضي عن هذه المنصة والدعم تمام الرضا وان شاء الله انصح جميع الذين يعانون من اي مرض يستطيع هذا المستشفى او المنصة تقديم المساعدة لهبالتواصل معهم على الفور واشكر دكتور يونس على اسلوبه الراقي ودعمه اللامحدود
San RaffaelePietro Mortini
Евгения • Stomach cancer surgery
Italy
Nov 7, 2018
Verified review.
"I declare with all responsibility that the San Rafael clinic in Milan is the best
The professionalism of the doctors, the newest equipment, the care of the clinic staff are among the best in Europe. The treatment and operations in Russia and Germany have been carried out, I declare with all responsibility that the San Rafael clinic in Milan is the best. After treating my father’s stomach cancer, I visited the neurologist and gastroenterologist and myself. Thank you so much to the coordinator, the doctors from the international department of the clinic. More in the world of such doctors. THANK YOU!
San Raffaele
Anonymous • Consultation with an oncologist
Russian Federation
Jan 2, 2020
Verified review.
We received a remote consultation at the San Rafael Clinic, for us this format was not suitable, because the second opinion is for those who either confirm the diagnosis or ask for another alternative treatment, we were told that after the consultation, continue the same, although we were treated and there was no result, as a result, after a remote consultation, we were not assigned anything, plus all communication was extended for a couple of months, because the clinic’s response rate was very low. We could not get any concrete answer, so this consultation was useless for us.
San Raffaele
Anonymous • Biopsy
Russian Federation
Feb 25, 2019
Verified review.
"Just returned from there
Just returned from there. Everything was top notch, and doctors, and the organization of the stay. It took 2 days from the first call to the bookmarked to my arrival in Milan. The next morning, consult a doctor. All questions were solved almost instantly, the results of all analyzes and studies were ready the next day. And constantly in touch with the coordinator Catherine and care worker Alexander. In my trips to the clinic, I was accompanied by a super translator Yulya Sukhneva. Thanks to the clear and professional work of Julia, Kati and Alexander, my stay was very short, I saved money on the hotel. The hotel, by the way, was excellent, up to the clinic, 200 meters. Yes, and more, the prices for consultations and analyzes are quite comparable with those in Moscow. I spent much less money than I thought at first. Thank you all!
San Raffaele
HALYNA NIKOLAIEVA • Melanoma
Ukraine
Jun 10, 2019
Verified review.
Thanks her
The doctor caused confidence and showed high professionalism, understood all the details and documents. She appointed the newest treatment. Satisfied with the service, Katerina Bonko was constantly in touch, showed attention and care. Thanks her.
About Bookimed service
I am satisfied with the service, Katerina Bonko was constantly in touch, showed attention and care. Thanks her.
San Raffaele
Anonymous • Consultation with an oncologist
Ukraine
Jun 29, 2022
Verified review.
- We were confirmed the same diagnosis that we received in Ukraine
We were confirmed the same diagnosis that we received in Ukraine. It was decided to continue treatment in Ukraine.
About Bookimed service
So
San Raffaele
Anonymous • Consultation with an oncologist
Italy
Jan 22, 2022
Verified review.
I would not hesitate to recommend Bookimed for enabling to have the required treatment
The Hospital handled my appointment and the paperwork promptly and efficiently. My outpatient contact with the Consultant was very professional. I would not hesitate to recommend Bookimed for enabling to have the required treatment.
About Bookimed service
Yes
San Raffaele

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Updated: 04/17/2026
Authored by
Anna Leonova
Anna Leonova
Head of Content Marketing Team
A certified medical writer with 10+ years of experience, developed Bookimed’s trusted content, backed by a Master’s in Philology and medical expert interviews worldwide.
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Reviewed by Bookimed Medical Advisor
Fahad Mawlood
Medical Editor & Data Scientist
General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
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This page may feature information relating to various medical conditions, treatments, and healthcare services available in different countries. Please be advised that the content is provided for informational purposes only and should not be construed as medical advice or guidance. Please consult with your doctor or a qualified medical professional before starting or changing medical treatment.

Fast Facts about Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

HIPEC involves delivering heated chemotherapy directly into the abdominal cavity to treat cancer.

Pros: HIPEC can target cancer cells more effectively within the abdomen compared to systemic chemotherapy. It has shown a 50% increase in survival rates for certain cancers.
Cons: This procedure may lead to more immediate side effects like abdominal pain and requires hospitalization for monitoring. Only suitable for cancers confined to the peritoneal cavity.
Effectiveness: 70% success rate in extending patient survival for specific peritoneal cancers.
Duration: 6-12 hours.
Recovery: 4-6 weeks.
Best for: Peritoneal carcinomatosis and abdominal tumors, especially those from colorectal and ovarian origins.
Prices: View costs of other techniques

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