Spain
All cities
Last updated: 10/3/2025

Immunotherapy in Spain: Our Best Clinics and Costs 2025

Why choose Spain for immunotherapy?

  • Accredited clinics: JCI-certified hospitals provide top-quality care and adhere to international standards.
  • Latest technologies: Spain employs methods such as CAR-T cell therapy and PD-1/PD-L1 inhibitors. These offer innovative treatment options for various cancers.
  • High success rates: Immunotherapy has shown an efficacy of 60-70% in treating melanoma and non-small cell lung cancer.
  • Expert surgeons: Leading oncologists, like Dr. Capdevila at Teknon Medical Centre, specialize in immunotherapy for colon cancer. They offer personalized treatment plans.

Access advanced Immunotherapy solutions in trusted clinics .

85 %
patient recommendation
46 K+
patients
820К+ patients have got assistance since 2014
50 countries
1,500 clinics
6K+ reviews
3K+ qualified doctors

How Much Does Immunotherapy Cost in Spain?

The cost of immunotherapy in Spain typically ranges from $12,000 to $25,000. Prices vary depending on the type of immunotherapy used (such as monoclonal antibodies, checkpoint inhibitors, or CAR-T cell therapy), the number of treatment cycles, the clinic, and the treating physician’s expertise. In the United States, the average price is $30,000 (according to the American Cancer Society). This means immunotherapy in Spain can be about 38% less than in the U.S.

Spanish clinics usually include initial consultation, diagnostic tests, medication administration, monitoring during treatment, and scheduled follow-up visits in the overall cost. In the U.S., the listed price often covers only the medication, with separate charges for doctor’s visits, lab tests, and infusion services. Always confirm exactly what’s included at each clinic.

TurkeyAustriaSpain
Immunotherapyfrom  $2,200from  $30,000from  $12,000
Sarcoma Immunotherapyfrom  $18,000from  $60,000from  $80,000
Immunotherapy for prostate cancerfrom  $12,000from  $30,000from  $35,000
Immunotherapy for lung cancerfrom  $18,000from  $30,000from  $30,000
Immunotherapy for breast cancerfrom  $9,500from  $35,000from  $45,000
The price research is based on updated and verified costs from the Bookimed partner clinics.

Your Benefits and Guarantees with Bookimed

Transparent Prices & Flexible Installments

No hidden fees – just official clinic prices. Pay at the clinic for Immunotherapy upon arrival and use a flexible installment plan if needed.

Verified Clinics & Doctors Only

Bookimed is committed to your safety. We only work with medical institutions that maintain high international standards in Immunotherapy and have the necessary licenses to serve international patients worldwide.

Free 24/7 Assistance

Bookimed offers free expert assistance. A personal medical coordinator supports you before, during, and after your treatment, solving any issues. You're never alone on your Immunotherapy journey.

Why we?

Your personal Bookimed medical coordinator

  • Supports you at every stage
  • Helps choose the right clinic and doctor
  • Ensures quick and convenient access to information

Discover the Best Immunotherapy Clinics in Spain: 8 Verified Options and Prices

The Bookimed clinic ranking is based on data science algorithms, providing a trusted, transparent, and objective comparison. It takes into account patient demand, review scores (both positive and negative), the frequency of updates to treatment options and prices, response speed, and clinic certifications.
Centro Médico Teknon

Centro Médico Teknon

Spain, Barcelona
Clinic is certified :
  • There are 10 kinds of immuno-drugs at Teknon Cancer Institute. This allows oncologists choosing the most appropriate vaccine for a certain tumor type and start treatment immediately.
  • Teknon takes the 1st place in Spain and 3rd in Europe by such criteria: patients’ recovery rate, doctors’ qualification, service quality.
  • Teknon cooperates with Memorial Sloan-Kettering Cancer Center, the leading medical facility in the USA. Together they develop and improve oncology treatment options.
4.7433 reviews
diagnostics
Gastroscopy with biopsy $1,203
PET/CT$2,564 - $4,080
treatment
Immunotherapy$4,000 - $5,000
Clinic's page
Quironsalud Madrid

Quironsalud Madrid

Spain, Madrid
Clinic is certified :
  • Recognized as one of the World's Best Hospitals 2021 by Newsweek for its exceptional care.
  • Offers immunotherapy as part of personalized cancer treatment plans to enhance the immune response.
  • Provides access to the latest cancer drugs, including immunodrugs, for effective tumor management.
  • Allows participation in clinical trials for potential free treatment, advancing cancer research.
  • Ensures patient comfort with private rooms equipped with necessary amenities for recovery.
3.86 reviews
diagnostics
Mammography $256
PET/CT$1,313 - $1,641
Clinic's page
SJD Barcelona Children’s Hospital

SJD Barcelona Children’s Hospital

Spain, Barcelona
Children & teens only (0-18)

Jaume Mora Graupera

29 years of experience
accreditations :
Clinic is certified :
4.841 reviews
Price on request
Clinic's page
Hospital Quiron Barcelona

Hospital Quiron Barcelona

Spain, Barcelona

Jesus Soberino

17 years of experience
accreditations :
Clinic is certified :
4.46 reviews
diagnostics
Gastroscopy with biopsy $1,212
PET/CT $1,807
Clinic's page
HM Hospitales

HM Hospitales

Spain, Madrid
Clinic is certified :
  • Recognized by the European Foundation for Quality Management, showcasing a commitment to excellence in healthcare.
  • Recipient of the TÜV AG Company Research & Investing Certificate, indicating high standards in clinical research and patient care.
  • Featured in Newsweek's World's Best Hospitals 2021, highlighting its international reputation.
  • Annually, the team serves approximately 75,000 inpatients and 2.3 million outpatients, ensuring vast experience in patient care.
  • Awarded by the Spanish Society of Health Informatics in 2018 for innovative patient care and healthcare technology solutions.
4.616 reviews
diagnostics
Biopsy $1,632
MRI of one area $699
Clinic's page

Immunotherapy in Spain: Your Travel Plan

Day 1: Arrival in Spain
  • Upon arrival, you should have all necessary documentation, including your passport, medical reports, and contact information. These are crucial for your initial consultation and clinic registration.
  • Settle into your accommodation and rest after your journey. You need to be well-rested for your upcoming consultation and treatment.
  • Familiarize yourself with the local area, including the clinic's location and nearby amenities you may need during your stay.
Day 2: Initial Consultation and Diagnostic Phase
  • Attend your scheduled consultation with the immunotherapy specialist. This meeting involves a thorough review of your medical history and previous treatments.
  • Undergo necessary diagnostic tests such as PET-CT, MRI, and blood analysis. These tests evaluate your eligibility for the treatment and tailor the CAR T-cell therapy to your needs.
  • Receive a detailed medical report and a personalized treatment plan outlining the recommended protocol and any pre-treatment requirements.
  • Discuss the estimated costs and any financial arrangements needed for your treatment.
Day 3-5: Preparation for Apheresis
  • Prepare for the apheresis procedure, which involves collecting your T-cells. This may include dietary adjustments or medication as advised by your medical team.
  • Attend any additional consultations or tests required to ensure you are ready for the procedure.
  • Maintain open communication with your medical team. Clarify any doubts or concerns you may have about the process.
Day 6: Apheresis Procedure
  • Undergo the apheresis procedure, which includes catheter insertion and leucapheresis. This is a critical step in collecting your T-cells for re-engineering.
  • Follow post-procedure care instructions carefully to ensure a smooth recovery. This may include rest and hydration.
  • Stay in touch with your medical team for any follow-up appointments or additional instructions.
Day 7-9: Rest and Monitoring
  • Take this time to rest and recover from the apheresis procedure. Your body needs to recuperate before the next phase of treatment.
  • Attend any scheduled follow-up appointments to monitor your recovery and ensure everything is on track for the CAR T-cell infusion.
  • Stay in contact with the clinic for any updates or changes in your treatment schedule.
Day 10-13: Pre-Treatment Chemotherapy (if required)
  • If pre-treatment chemotherapy is part of your protocol, begin this phase as scheduled. This step helps prepare your body for the CAR T-cell infusion.
  • Follow all medication and dietary guidelines provided by your medical team to minimize side effects and enhance treatment efficacy.
  • Keep your medical team informed of any side effects or concerns during this phase.
Day 14: CAR T-Cell Infusion
  • Undergo the CAR T-cell infusion, a pivotal part of your treatment. The re-engineered T-cells are infused back into your body to target and destroy cancer cells.
  • Expect to stay in the hospital for monitoring and care, including potential ICU care if needed. Medications like Tocilizumab may be administered to manage any side effects.
  • Communicate regularly with your medical team about how you are feeling and any symptoms you experience.
Day 15-44: Hospitalization and Monitoring
  • Remain in the hospital for up to 30 days for observation and care. This period is crucial for monitoring your response to the treatment and managing any side effects.
  • Participate in regular check-ups and tests, such as PET-CT and bloodwork, to evaluate the therapy's effectiveness.
  • Utilize translator-assistant services if necessary to ensure clear communication with your medical team.
  • Stay connected with family and friends for emotional support during your hospital stay.
Day 45-60: Post-Treatment Follow-Up

Our Trusted Doctors

View all Doctors
verified

Jesus Soberino

17 years of experience

Dr. Jesus Soberino is an oncologist at Vall d’Hebron University Hospital and the Vall d’Hebron Institute of Oncology (VHIO). He specializes in breast cancer and melanoma. Dr. Soberino has led many phase 1–3 clinical trials. His work has helped approve important drugs, including CDK4/6 inhibitors for metastatic breast cancer and immunotherapies for melanoma.

His areas of expertise include endocrine therapy, managing hormone resistance, and developing new immunotherapies. Dr. Soberino is known for his patient-centered care. He actively collaborates in research to improve cancer treatment. He is accredited by VHIO and is a key member of the Breast Cancer and Melanoma Units.

verified

Francesc Graus

43 years of experience
  • Specializes in immune checkpoint inhibitors for cancer-related neurotoxicities.
  • Trained in Neurology and Neuro-Oncology in Spain and the USA.
  • Founder and past president of the European Association of Neuro-Oncology.
  • PhD from Universitat Autónoma de Barcelona, certified in Neurology.
  • Emeritus investigator at IDIBAPS, focusing on neuroimmunological research.
verified

Jaume Mora Graupera

29 years of experience

Dr. Jaume Mora Graupera is a pediatric oncologist specializing in the treatment of neuroblastomas, gliomas, Ewing's sarcomas, and Wilms' tumors. He is the Director of the Hematology Oncology Department and Developmental Tumors Laboratory at Sant Joan De Déu - Barcelona Children’s Hospital. He received his medical degree from the University of Barcelona, went on to complete specialty training in pediatrics and fellowships in pediatric hematology oncology and molecular pathology of pediatric cancer at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center in the USA. He has won multiple awards and is a member of various medical organizations.

verified

Francesc Bosch

125 years of experience

Dr. Francesc Bosch is an expert in Chronic Lymphocytic Leukemia (CLL) and lymphomas. He leads research in the molecular causes and new treatments for CLL and other lymphoproliferative disorders.

He has published over 100 articles in leading journals, including The New England Journal of Medicine and Nature Medicine. Dr. Bosch oversees more than 80 clinical studies, from phase 1 to phase 3, and plays a key role in developing new drugs.

He is the Head of Hematology at Vall d’Hebron University Hospital and IOB Institute of Oncology. He also serves as president of GELLC and is a professor of hematology. His work has improved diagnosis and treatment for blood diseases.

Video Stories from Bookimed Patients

Amanda
My companion and I were treated with such kindness — I have nothing but admiration for the entire team.
Procedure: Mastectomy
Clinic: Lokman Hekim Istanbul Hospital
Randolph
Stay strong, stay informed, and never underestimate the power of cutting-edge treatments and a solid support system.
Procedure: Radioembolization for liver cancer
Clinic: Confraternitaet Private Hospital

Reviews about Bookimed: Discover Patients' Insights

All reviews
Mansour • Sigmoid adenocarcinoma
Pakistan
Nov 8, 2023
Verified review.
As a doctor I recommend bookimed
I introduced many patients to other medical tourism companies but most of them were not honest such as Bookinghealth.com they did fraud with our patients so finally I found an excellent company by the name of bookimed.com Iam the client Of bookimed.com since 5 years and all of my patients are satisfied from its staffs and services so as a doctor I recommend bookimed.com to choose as a right a guaranteed company in the term of your health …. Best wishes Dr.Mansoor
Centro Médico Teknon
Anonymous • Colon cancer
Sweden
Mar 27, 2025
Verified review.
Overall, I had a positive experience and would recommend it to others
My online consultation experience was very smooth and professional. The medical team was knowledgeable, attentive, and answered all my questions thoroughly. The platform was easy to use, and I appreciated the quick response time. Overall, I had a positive experience and would recommend it to others
- I really appreciated the professionalism and kindness of the medical team. They made me feel comfortable and well cared for. - The consultation was quick and efficient, and the doctor provided clear and helpful advice. - I liked how easy it was to book an appointment and how responsive the team was. - The detailed explanations and personalized care were the best parts of my experience.
About Bookimed service
My experience with Bookimed was excellent. The platform made it easy to find and connect with a medical specialist. The support team was very responsive and guided me throughout the process. The consultation was professional, and the doctor provided clear and helpful advice. I would definitely recommend Bookimed to others seeking medical assistance.
Centro Médico Teknon
Natalia Rayskiy • Online Consultation with Oncologist
Belarus
Dec 30, 2019
Verified review.
Мы очень довольны клиникой Sant Joan de Deu, в которой наблюдается наш ребёнок
Мы очень довольны клиникой Sant Joan de Deu, в которой наблюдается наш ребёнок. Хочется отметить высокий профессионализм доктора Мора и медицинского персонала. Рекомендуем эту детскую клинику для обследования и лечения. Также хочется отдельно поблагодарить медицинского координатора Ангелину Иваненко, которая и помогла нам принять верное решение в выборе клиники.Ангелина и на сегодняшний день помогает оперативно решать все вопросы, всегда на связи. Именно она предложила нам провести скайп консультацию с врачом. Огромное преимущество данной консультации - экономия времени, когда необходимо получить мнение компетентного врача и двигаться дальше в обследовании.Bookimed мы выбрали случайно, и не жалеем об этом.Всем рекомендуем.
SJD Barcelona Children’s HospitalJaume Català Mora
Надежда Sergiyenko • Ovarian cancer
Ukraine
Jun 11, 2019
Verified review.
The format is quite simple, everything is accessible and understandable, the doctor is very qualified. I will not say that we talked about clinical studies, there was no definitive information. We are happy, time has been spent, the translator also translated everything correctly. The doctor explained everything popularly, we received an answer to all the questions we asked. I believe that what you are doing is very important and useful for people who need help.
Hospital Quiron Barcelona
Karen • Mammography
United States of America
May 17, 2022
Verified review.
I saw Dr
From the minute I was inquiring about an appointment through to an entire 2 hours of tests, I felt completely taken care of. Being in a foreign country where it’s not your first language can be daunting when needing healthcare. My healthcare navigator Leen was so wonderful. She brought me to each doctor or department, got me situated and was also my translator. She was kind, compassionate & so incredibly helpful. I was incredibly grateful to have her by my side. I saw Dr. Bassols who was incredibly warm, knowledgeable and put my fears at ease. The other technicians were also wonderful and caring. I highly recommend the staff and care I received at Centro Medico Teknon and the team from bookimed that connected me to them. Thank you everyone!!
About Bookimed service
Yes!
Centro Médico Teknon
Charlene • Bone marrow transplantation
Spain
May 23, 2022
Verified review.
The doctor (Madero) didn’t even respond to our greetings when we entered his office. He didn’t even read correctly the medical report. He didn’t explained anything. He was doing things in a rush as if we didn’t have an appointment with him. He even left us in his office and went away. We were so frustrated after the consultation. Coming from Cameroon for this, was so disappointed.
About Bookimed service
Yes, Bookimed did a good job. After our misadventure with quironsalud Madrid, the medical coordinator booked us another appointment with Clinica Universidad de Navarra. The appointment went well and we were sarisfied of the hospital services.
Quironsalud MadridLuis Madero
Алена • Online Consultation with Pediatric Oncologist
Germany
Dec 18, 2023
Verified review.
The coordinator Yulia is an excellent specialist
I would like to thank the Bookimed team for the perfectly organized consultation with the doctor. The coordinator Yulia is an excellent specialist, I felt support at all stages!
I liked absolutely everything, starting from the first application on the site, consultation with specialist Yulia and further support. Julia was always in touch, I received answers to my questions on time. The meeting with the doctor and translator was perfectly organized, taking into account all our wishes!
SJD Barcelona Children’s Hospital
Ірина • Tongue cancer
Ukraine
Apr 7, 2023
Verified review.
Все було чітко й зрозуміло
About Bookimed service
Молодець!!!!
Centro Médico Teknon
Anonymous
Kyrgyzstan
Feb 1, 2020
Verified review.
-Let me express my deepest gratitude for your care, admiration of your greatest talent and your positive, super-nice personality!
Dear amazing Dr. Bartolomé Oliver! Let me express my deepest gratitude for your care, admiration of your greatest talent and your positive, super-nice personality! I was so lucky to be in hands of one of the most experienced and the BEST doctors in the world!!! You made rare and complicated surgery look easy! My whole year full of stress, fear is over thanks to you! Live the longest and happiest life! All the best wishes to you! Thank you! Doctor!!! Thanks to your team! Thanks to International department and my bookimed coordinator-Dr. Kamran Abbas-Zade! Your “C7 Neurunoma” patient
About Bookimed service
Absolutely satisfied! Dr Kamran Abbas-Zade guided me through the whole process, and brought me to the best doctor in the world! communication level was great, replies were quick. Olga was caring and initiative, helped me solve my migraine issue.
Centro Médico TeknonBartolomé Oliver
Наталья • Breast cancer
Ukraine
Sep 25, 2019
Verified review.
- Thank!
I turned to Bookimed for a second independent opinion, I didn’t expect anything, but I was pleasantly surprised by the speed and cramming of the coordinating doctors Katya Koliko and Olga Krisyuk. We organized a video consultation with the HM clinic in Spain, everything went as planned, the doctor wrote what needs to be done at the moment and treatment options. Thank !
HM Hospitales

Related Articles

Share this content

Twitter XLinkedinFacebookWhatsAppEmail
Get link
Updated: 03/27/2025
Authored by
Anna Leonova
Anna Leonova
Head of Content Marketing Team
A certified medical writer with 10+ years of experience, developed Bookimed’s trusted content, backed by a Master’s in Philology and medical expert interviews worldwide.
Anna Leonova Linkedin
Reviewed by Bookimed Medical Advisor
Fahad Mawlood
Medical Editor & Data Scientist
General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
Fahad Mawlood Linkedin
This page may feature information relating to various medical conditions, treatments, and healthcare services available in different countries. Please be advised that the content is provided for informational purposes only and should not be construed as medical advice or guidance. Please consult with your doctor or a qualified medical professional before starting or changing medical treatment.

Our Immunotherapy Techniques: What Suits You Best?

When considering Immunotherapy, it’s important to understand the different techniques and which is best suited for you. Here’s a concise comparison of popular options:

Immunotherapy with Keytruda (Pembolizumab)

Keytruda, a form of immune-based therapy, leverages the body's immune system to target and destroy cancer cells using monoclonal antibodies.

Pros: Offers a targeted approach with fewer side effects; clinical trials show a 70% response rate in some cancers. Suitable for varied cancer types due to its immune modulation properties.
Cons: May cause immune-related adverse effects such as colitis or pneumonitis in up to 10% of patients. Limited effectiveness in tumors with low PD-L1 expression.
Effectiveness: 70% response rate in some cancer types.
Duration: Each session lasts about 30 minutes.
Recovery: Not needed.
Best for: Cancers with high PD-L1 expression, melanoma, and non-small cell lung cancer.
Prices: Cost of Immunotherapy with Keytruda (Pembolizumab) in Spain from $15,000

CAR T-cell therapy

CAR T-cell therapy is a personalized immune system therapy that modifies a patient's T-cells to target and destroy cancer cells.

Pros: This immune-based therapy offers a high remission rate of up to 90% in certain blood cancers. It provides long-lasting effects by boosting the immune system's ability to combat cancer.
Cons: It can cause severe side effects like cytokine release syndrome in up to 50% of patients. This biotherapy is complex and not suitable for solid tumors.
Effectiveness: 80% remission rate in certain leukemia and lymphoma cases.
Duration: 2-3 weeks.
Recovery: 1-2 months.
Best for: Blood cancers like acute lymphoblastic leukemia and diffuse large B-cell lymphoma.
Prices: Cost of CAR T-cell therapy in Spain from $330,000

Get a free consultation

Select the best way to contact you