Best Hospitals for Liver cancer treatment in the World 2025

On this page, you will find the top-rated clinics and prices for Liver cancer treatment. The ranking is based on patient choices at Bookimed, verified reviews, clinic performance, and expert evaluations, ensuring you have access to trusted and high-quality options.

How much do Liver cancer diagnostic and treatment procedures cost?

The cost of liver cancer treatment can range from $13,550 to $33,660:

  • Turkey: CyberKnife from $5,630 to $8,070, NanoKnife from $6,380 to $11,520, Proton-beam therapy from $10,000 to $50,000.
  • Israel: CyberKnife from $11,100 to $18,600, NanoKnife from $10,500 to $21,700, Proton-beam therapy from $30,000 to $100,000.
  • South Korea: CyberKnife from $4,800 to $9,400, Proton-beam therapy from $30,000 to $50,000.

The doctor will determine the total treatment cost based on your needs and past treatments. You may not need to redo previous tests, which could save money.

The price research is based on updated and verified costs from the Bookimed partner clinics.

Best Liver cancer treatment centers in Turkey

Turkey provides specialized liver cancer treatment through facilities accredited by the Joint Commission International, including Anadolu Medical Center, Memorial Şişli Hospital, and Hisar Hospital Intercontinental. Anadolu Medical Center, affiliated with Johns Hopkins Hospital, utilizes advanced imaging-guided procedures for hepatocellular carcinoma. Memorial Şişli Hospital, the first in Turkey with JCI accreditation, has achieved a 90% success rate in liver transplantation procedures.

Turkish oncology centers report five-year survival rates of 65% for early-stage hepatocellular carcinoma through radiofrequency ablation, transarterial chemoembolization, targeted molecular therapy, and immunotherapy. For Barcelona Clinic Liver Cancer stage 0-A patients receiving curative treatments, one-year survival rates exceed 80%. Hisar Hospital Intercontinental specializes in minimally invasive procedures that reduce recovery time while maintaining treatment efficacy for selected liver cancer patients.

Anadolu Medical Center
Memorial Şişli Hospital

Memorial Şişli Hospital

Turkey, Istanbul
Clinic is certified :
Hisar Hospital Intercontinental

Best Liver cancer treatment centers in Germany

Germany excels in liver cancer treatment with leading hospitals such as Asklepios Hospital Barmbek, Nordwest Clinic (Krankenhaus), and Medical Center in Solingen. Accredited by the German Cancer Society (DKG), they offer advanced procedures like transarterial chemoembolization (TACE), radiofrequency ablation (RFA), stereotactic body radiotherapy (SBRT), and liver transplantation. These treatments, combined with targeted therapies and immunotherapy, improve patient outcomes.

Asklepios Hospital Barmbek treats 80,000 patients annually, accredited by the International Organization for Standardization. Nordwest Clinic (Krankenhaus) is known for innovations like 3D ultrasound, while Medical Center in Solingen treats over 60,000 patients per year. In Germany, procedures like liver resection show a high success rate of approximately 85% for early-stage liver cancer patients. This highlights the effectiveness of treatment options available in the country.

Asklepios Hospital Barmbek
Nordwest Clinic (Krankenhaus)

Best Liver cancer treatment centers in Spain

Spain offers advanced liver cancer treatment through medical institutions accredited by the Joint Commission International. Leading facilities include Centro Médico Teknon, Quironsalud Madrid, and SJD Barcelona Children's Hospital. Centro Médico Teknon specializes in minimally invasive hepatic procedures, while Quironsalud Madrid conducts ongoing clinical trials in hepatocellular carcinoma. SJD Barcelona Children's Hospital focuses on pediatric liver tumors with a multidisciplinary approach.

Spanish oncology centers achieve five-year survival rates of 70% for early-stage hepatocellular carcinoma through treatments including transarterial chemoembolization (TACE), stereotactic body radiation therapy, radiofrequency ablation, and molecularly targeted therapies. For patients with Barcelona Clinic Liver Cancer stage A disease who receive surgical resection, the survival rate improves to 65-70%, compared to the European average of 47% across all stages. Quironsalud Madrid's liver transplantation program has documented one-year survival rates exceeding 85% for carefully selected patients.

Hospital Quiron Barcelona

Hospital Quiron Barcelona

Spain, Barcelona
Clinic is certified :

Best Liver cancer treatment centers in Israel

Israel is renowned for its advanced liver cancer treatment, with leading medical centers such as Sourasky Medical Center (Ichilov), Assuta Medical Center, and Hadassah Medical Center. Sourasky Medical Center (Ichilov), recognized among the Top 10 most popular clinics for medical tourists globally, boasts a 90% average success rate in oncology treatment. Assuta Medical Center, accredited by Joint Commission International, emphasizes personalized care. Hadassah Medical Center in Jerusalem is celebrated for its excellence in oncology and other specialties.

Advanced procedures for liver cancer treatment in Israel include radiofrequency ablation, transarterial chemoembolization (TACE), selective internal radiation therapy (SIRT), and liver transplantation. These techniques contribute to the country's high liver cancer survival rates, with approximately 85%-90% of patients achieving positive treatment outcomes. The focus on precise diagnostics and personalized treatment plans ensures that patients receive the most effective care possible.

Sourasky Medical Center (Ichilov)
Assuta Medical Center

Assuta Medical Center

Israel, Tel Aviv
Clinic is certified :

The surgeons apply an innovative surgical method of IRE (Irreversible Electroporation) or NanoKnife, as well as the Intrabeam System (intraoperative radiation). These original methods do not require application of a scalpel as far they are targeted and dotted methods of liver cancer treatment. For instance, NanoKnife is characterized by minimal injury rate and high-precision performance, minimizing postsurgical complications for the patient. Oncologists use it to destroy cancer cells under the impact of specific electrical impulses.

Main surgical methods of liver cancer treatment in Assuta are the following:

  • At the 1-2 stages of cancer with a small tumor and without metastasis resection is performed by means of Irreversible Electroporation (IRE) or NanoKnife.
  • At the 2 and 3 stages of liver cancer wide excision of the liver (about its half) - hemihepatectomy - is conducted.
  • At the severe stage of the disease the removal of the liver, duodenum, part of the stomach and pancreas are carried.
  • Complete liver transplantation.

Best Liver cancer treatment centers in Austria

Austria excels in liver cancer treatment, with leading facilities like Confraternitaet Private Hospital, Wiener Privatklinik, and Vienna General Hospital (AKH). Wiener Privatklinik, accredited by the International Organization for Standardization, is known for its innovative practices. Vienna General Hospital (AKH) offers advanced technology and skilled care, making it a leader in liver cancer treatment.

Austria offers liver cancer procedures like radiofrequency ablation, TACE, SIRT, and liver transplantation. With a focus on early detection and treatment, Austrian hospitals report success rates of approximately 70-75% for patients diagnosed at an early stage. Confraternitaet Private Hospital provides a multi-stage care system, while AKH is noted for its high standards and innovation.

Top Liver cancer treatment clinics in the world

  • Anadolu Medical Center, Turkey
  • Memorial Şişli Hospital, Turkey
  • Hisar Hospital Intercontinental, Turkey
  • Asklepios Hospital Barmbek, Germany
  • Nordwest Clinic (Krankenhaus), Germany
  • Medical Center in Solingen, Germany
  • Centro Médico Teknon, Spain
  • Hospital Quiron Barcelona, Spain
  • Quironsalud Madrid, Spain
  • Sourasky Medical Center (Ichilov), Israel
  • Assuta Medical Center, Israel
  • Hadassah Medical Center, Israel
  • Confraternitaet Private Hospital, Austria
  • Wiener Privatklinik, Austria
  • Vienna General Hospital (AKH), Austria
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Authored by
Anna Leonova
Anna Leonova
Head of Content Marketing Team
A certified medical writer with 10+ years of experience, developed Bookimed’s trusted content, backed by a Master’s in Philology and medical expert interviews worldwide.
Fahad Mawlood
Medical Editor & Data Scientist
General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
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All You Need to Know about Liver cancer

What Is Liver Cancer?

Liver cancer, also known as hepatocellular carcinoma (HCC), is a severe condition that develops when abnormal cells in the liver grow uncontrollably and compromise the immune system. These tumors can disrupt normal liver function and can be life-threatening if left untreated.

The liver is a vital organ responsible for various functions, including:

  • Filtering toxins from the blood;

  • Producing proteins;

  • Storing nutrients.

Liver cancer has two main types based on a malignancy location:

  • 🔺Primary liver cancer derives from liver cells;

  • 🔻Secondary liver cancer is a metastasis of a tumor from a different location.

faq image

Primary liver cancer accounts for about 2% of all cancers in the U.S. and affects twice as many men as women, with an average age of diagnosis at 67. It has two main subtypes:

  • 🔬 Hepatocellular carcinoma (HCC) is the most common type, accounting for about 90% of all liver cancers. It originates in the primary type of liver cells called hepatocytes.

  • 🔬 Intrahepatic cholangiocarcinoma (ICC) is a less common type that starts in the bile ducts responsible for transporting bile, a digestive fluid. The doctors call this type "bile duct cancer".

Liver cancer can affect people of all ages, but it's more common in individuals with certain risk factors.

What Are the Risk Factors for Liver Cancer?

The main risk factors of primary liver cancer include having hepatitis B or hepatitis C. These diseases are destroying liver cells, increasing their chances for mutation. Several other factors can increase a person's risk of developing liver cancer.

faq image

These include:

Cirrhosis

Cirrhosis, the scarring of liver tissue due to long-term damage, significantly increases the risk of liver cancer. When the liver attempts to repair itself repeatedly, scar tissue formation impairs its function and elevates the likelihood of emerging tumor cells.

Patients with cirrhosis, regardless of the underlying cause, are typically under surveillance for liver cancer, as they are at a higher risk of developing HCC.

Lifestyle Factors

Liver cancer specialists claim that heavy alcohol consumption over time can cause liver inflammation and damage, leading to cirrhosis and an increased likelihood of cancer development.

Obesity is another critical risk factor, as it is associated with nonalcoholic fatty liver disease (NAFLD), which can progress to cirrhosis and liver cancer. Additionally, smoking has been linked to a higher risk of liver cancer, as the harmful chemicals in tobacco can contribute to liver damage over time.

Genetic Factors

Hemochromatosis, a disorder where the body absorbs too much iron, can lead to iron buildup in the liver, causing cirrhosis and increasing cancer risk. Another genetic disorder, alpha-1 antitrypsin deficiency, can result in liver disease, particularly in children and young adults, by causing abnormal protein accumulation in the liver cells, leading to cirrhosis.

Exposure to Toxins

Chronic exposure to certain toxins significantly heightens the risk of liver cancer. Aflatoxins, produced by a specific mold that grows on improperly stored grains and nuts, are a well-known carcinogen, particularly in developing countries with poor food safety practices.

Plus, industrial chemicals like vinyl chloride, used in plastics manufacturing, have been linked to liver tumors. Individuals working in industries with chemical exposure or those living in areas with poor food safety measures are at a heightened risk for developing liver tumors.

What Are the Symptoms of Primary Liver Cancer?

Early-stage tumor often presents with no noticeable symptoms. However, as the cancer progresses, some potential signs and symptoms include:

  • Unexplained weight loss;

  • Loss of appetite;

  • Fatigue;

  • Nausea and vomiting;

  • Abdominal pain or swelling in the upper right abdomen;

  • Jaundice (yellowing of the skin and eyes);

  • Enlarged liver (hepatomegaly);

  • Dark-colored urine.

*Please note that the symptoms mentioned above could indicate other conditions. Contact a Bookimed coordinator to consult with a liver cancer oncologist. Our medical advisors are available to assist you, either online or offline, based on your preference.

How Is Liver Cancer Staged?

The Barcelona Clinic Liver Cancer (BCLC) system is a widely used method. It categorizes liver tumors based on several factors, such as:

  • Tumor size and number of tumors;

  • Preserved liver function;

  • Presence of vascular invasion (whether cancer has spread to blood vessels).

The BCLC staging system has five stages:

  • 🟡 stage 0: very early;

  • 🟡 stage A: early;

  • 🟡 stage B: intermediate;

  • 🟡 stage C: advanced;

  • 🟡 stage D: end-stage.

What Are the Treatment Approaches?

Every patient needs a personalized treatment plan according to the cancer's stage, severity of symptoms, etc. The National Cancer Institute recommends the following treatment options:

Therapy

Options

Benefits

Risks/side effects

Surgery

Complete removal of tumor (hepatectomy), a portion of the liver (resection), or performing a liver transplant in suitable cases.

Removing the tumor in the early stages.

Bleeding, infection, and damage to surrounding organs.

Liver ablation

A minimally invasive technique that destroys cancer cells using heat, radiofrequency, or freezing.

  • Radiofrequency ablation;

  • Microwave ablation;

  • Cryoablation, etc.

Allows for faster recovery and fewer complications compared to open surgery. It can be effective for small, localized tumors.

Pain, bleeding, and infection.

Embolization therapy

This is for patients without metastases unsuitable for surgery or ablation. The doctor inserts a catheter into the hepatic artery to stop the blood supply of hepatocellular carcinoma.

Reduces blood flow to the tumor, potentially slowing its growth and minimizing symptoms.

Indirect damage of healthy tissues due to intended blockage of blood vessels.

Chemotherapy

Drugs such as Gemzar or Eloxatin can be used to treat liver cancer. Although most chemo medicines do not have a significant effect on liver tumors, doctors use them in combination with other treatments.

Clears out mutated cells, controlling cancer spread.

Nausea, vomiting, hair loss, and fatigue.

Radiation therapy

The external device sends high-energy X-rays toward the damaged area.

  • Conformal radiation therapy shapes the radiation beams to fit the tumor;

  • Stereotactic body radiation therapy places patients in the same position every time to reduce damaging healthy tissues;

  • Proton therapy sends streams of protons for effective tumor removal.

Quickly destroying the malignant area, reducing the potential of cancer spread.

Fatigue, skin irritation, and digestive problems.

Targeted therapy

Drugs like bevacizumab, cabozantinib, and lenvatinib attack specific tumor cells. They block critical proteins for cell growth inducing remission.

Selectively targets cancer cells, minimizing damage to healthy tissues.

High blood pressure, fatigue, and skin problems.

How to Choose Treatment Based on Cancer's Stage?

Here's a breakdown of hepatocellular carcinoma stages alongside the suitable plans:

Stage

Definition

BCLC group

Treatment Method

Localized

The cancer is confined to the liver.

0, A, and B.

Surgery

Locally advanced

The cancer has not spread to distant organs but cannot be safely removed by surgery.

C

Chemotherapy, proton therapy, and targeted therapies.

Metastatic

The cancer has spread to distant parts of the body.

D

Palliative treatment strategy.

Recurrent

The cancer has returned after initial treatment.

-

Combination of therapies, depending on the severity of symptoms and test results.

Some patients opt to participate in clinical trials. They can benefit from testing a new drug for free or try out new experimental treatments.

What Countries Have the Best Liver Cancer Treatment Centers?

Choosing the right medical facility for liver cancer can significantly impact the treatment experience and outcomes. Here's the list of countries with the  best liver cancer treatment centers in the world.

🇹🇷 Turkey

Pros:

  • Affordability. Offers competitive pricing compared to many Western countries.

  • Advanced Technology. Equipped with modern medical facilities and technology.

  • Experienced Oncologists. The country has a growing number of skilled specialists in liver cancer treatment.

  • Cultural Familiarity. It may be more comfortable for English-speaking patients.

Cons:

  • Language Barriers. While English is widely spoken in major cities, communication challenges may exist in some regions.

  • Infrastructure. While improving, the healthcare infrastructure in some areas may not be as advanced as in Western countries.

🇮🇱 Israel

Pros:

  • Innovative Research. Known for medical advancements and cutting-edge treatments.

  • Personalized Care. Focuses on tailored treatment plans for individual patients.

  • High Standards. Adheres to strict international standards of care.

Cons:

  • Cost. Treatment in Israel may be more expensive compared to some other countries.

  • Language Barriers. While English is widely spoken, language challenges may exist.

🇩🇪 Germany

Pros:

  • World-Class Expertise. Renowned for excellence in medical care, particularly oncology.

  • Advanced Technology. Equipped with the latest medical equipment and facilities.

  • Comprehensive Care. Offers a wide range of services, including diagnostics, treatment, and aftercare.

Cons:

  • Cost. The treatment costs are higher, especially for private healthcare.

  • Language Barriers. While English is spoken in many areas, language challenges may exist.

🇪🇸 Spain

Pros:

  • Pleasant Climate. Mediterranean climate can contribute to a positive recovery experience.

  • Cultural Diversity. Offers a welcoming environment for international patients.

  • High-Quality Healthcare. The country adheres to international standards of care.

Cons:

  • Language Barriers. While English is widely spoken in tourist areas, language challenges may exist in some regions.

  • Cost. Treatment can be more expensive than in some other countries, especially for private healthcare.

🇦🇹 Austria

Pros:

  • High-Quality Care. Austria is famous for its robust healthcare system.

  • Beautiful Scenery. Can contribute to a positive recovery experience.

  • Modern Infrastructure. Has well-developed healthcare facilities and experienced professionals.

Cons:

  • Cost. Treating cancer in Austria would cost more, especially for private healthcare.

  • Language Barriers. While English is spoken in many areas, language challenges may exist.

Choosing the  best hospital to treat liver cancer is paramount for successful treatment. Look out for medical facilities with a proven track record in liver cancer care and positive patient reviews.

If you're running out of time and want to find the best hospital for liver cancer, contact the Bookimed coordinator. We'll find the cancer center based on your history and symptoms.

How to Find the Best Oncologist for Liver Cancer?

When facing a diagnosis of liver cancer, selecting the best possible treatment center is paramount. The right choice can significantly impact your treatment experience and outcomes. Here are some key factors to consider:

Expertise and Experience:

  • Specialization in Liver Cancer. These specialists have in-depth knowledge and experience in managing this complex disease.
  • Number of Cases. Consider oncologists with a history of successful outcomes in liver cancer treatment.
  • Board-Certified Specialists. The best liver cancer doctors should have board certifications in medical oncology and be accredited by reputable organizations, such as the Joint Commission International (JCI).

The best doctors work at renowned medical centers. Remember that Bookimed can also advise the  best place to treat liver cancer based on your individual history. Contact us for more information.

References

Key Statistics About Liver Cancer. Information and Resources about Cancer: Breast, Colon, Lung, Prostate, Skin | American Cancer Society. URL: https://www.cancer.org/cancer/types/liver-cancer/about/what-is-key-statistics.html (date of access: 04.10.2024).

Liver Cancer Risk Factors | Risk of Liver Cancer. Information and Resources about Cancer: Breast, Colon, Lung, Prostate, Skin | American Cancer Society. URL: https://www.cancer.org/cancer/types/liver-cancer/causes-risks-prevention/risk-factors.html (date of access: 04.10.2024).

Liver Cancer Treatment. Comprehensive Cancer Information - NCI. URL: https://www.cancer.gov/types/liver/what-is-liver-cancer/treatment (date of access: 04.10.2024).

Prevalence and characteristics of hepatitis C virus-related hepatocellular carcinoma in a Spanish university hospital. Cancer Epidemiology. URL: https://www.sciencedirect.com/science/article/abs/pii/S1877782122000479 (date of access 04.10.2024)