Patients with a body mass index below 18.5 often lack sufficient donor fat for successful harvesting and transfer. Chronic smokers, individuals with uncontrolled diabetes, and those with active autoimmune diseases face high graft failure rates due to impaired blood circulation and systemic inflammation.
- Low body fat: Patients with under 15% body fat cannot sustain long-term graft volume.
- Nicotine use: Smoking or vaping causes blood vessel constriction and near-total fat loss.
- Weight instability: Frequent fluctuations or active weight loss plans ruin final aesthetic results.
- Medical history: Uncontrolled diabetes or autoimmune disorders often lead to complete graft dissolution.
Bookimed Expert Insight: While many clinics offer standard fat grafting, Korean centers like RNWOOD Plastic Surgery specialize in advanced nanofat and stem cell techniques. Data shows these methods are specifically designed to improve the 50% resorption rate common in traditional lipofilling. Patients with thin skin or those over 50 should prioritize these cell-enriched options to avoid the visible lumps or orange-peel textures seen in basic procedures.
Patient Consensus: Many emphasize that results are not a one-time fix, as 30% to 50% of volume typically disappears within months. Patients frequently recommend maintaining a stable weight and quitting nicotine 3 months early to prevent total resorption.