Best Proton-beam therapy Clinics and Costs in 2025

How to choose the right proton beam center for effective treatment?

In this section we'll illuminate the major points before choosing appropriate proton radiation therapy centers for cancer treatment. So, keep in mind these aspects before making a thought-out decision.

• Accreditation and certification availability

As usual, accredited and certified medical entities adhere to strict standards and deliver high-quality patient care. Such respected centers have a team of specialized oncologists and feature cutting-edge technologies, guaranteeing diagnostic precision.

For instance, the National Cancer Institute (NCI), American College of Radiology (ACR), and Commission on Cancer (CoC) accreditations are among the most trustworthy in the area of cancer treatment.

• Expert-level medical team

The clinic's expertise is enhanced by the availability of experienced and well-trained oncologists, surgeons, nurses, and support staff. Skillful doctors contribute significantly to developing personalized treatment plans.

• Advanced technologies

State-of-the-art equipment is another crucial aspect indicating the high level of the hospital, which deals with cancer treatment.

Accredited cancer centers invest in advanced imaging, radiation therapy, and surgical technologies to provide precise and targeted interventions.

• All-inclusive cancer care programs

Beyond medical treatments, comprehensive cancer care includes emotional and practical support. Cancer centers offer a range of support services, such as counseling, support groups, social workers, and survivorship programs, to address the holistic needs of patients. This holistic approach often leads to a better quality of life.

What are the features of leading proton beam therapy centers?

The world's major PBT centers can be distinguished by high-tech medical facilities, a team of professional oncologists and radiologists, and all-inclusive patient care. Here is a detailed overview of these characteristics:

✅ Applying advanced technologies

Radiation therapy and proton one, in particular, require utilizing cutting-edge radiation equipment to guarantee patients precise results and overall cancer treatment. Such state-of-the-art systems include:

• pencil beam scanning (PBS), where a narrow proton beam paints the tumor layer by layer, reducing damage to surrounding healthy tissue;

• image-guided proton therapy (IGPT), which combines imaging technologies like CT, MRI, and X-ray to guide proton delivery;

• 4D imaging to track tumors that move through respiration (lung or liver tumors), ensuring precise targeting;

• intensity-modulated proton therapy (IMPT) that adjusts the intensity of the proton beams;

• multi-room facilities, such as treatment rooms with gantries for 360-degree beam delivery.

✅ Broad expertise level

Cancer treatment requires a strong team of skillful and trained doctors in various fields of oncology. The list of specialists involves radiation oncologists, medical physicists, dosimetrists, specialized nursing staff, etc.

✅ Broad experience in cancer treatment

Highly specialized doctors should know proper treatment plans for rare and complex cases, including brain, spinal, and pediatric cancers.

✅ Availability of clinical trials and conducting research

Big cancer centers are involved in clinical research and support innovative treatments and protocols.

✅ Broad treatment capabilities

Advanced proton beam centers should be able to treat different types of cancer, have special treatment programs for children, and treat benign tumors.

✅ All-inclusive patient-oriented support

Such centers should provide psychological consultations, nutrition planning, physical therapy, and extra counseling with other specialists.

✅ Global reputation and recognition

The availability of recognized certifications from organizations like the Joint Commission (JCI) or the American College of Radiology (ACR) means that a proton beam centre follows high patient care standards. Additionally, collaboration and partnership with the world's academic institutions promote the implementation of innovations and foster training for new oncology specialists.

➡️ With Bookimed, you can be sure that you’ll get into a decent PBT center. Your medical coordinator will help you to arrange your treatment quickly just within 2-7 days. Since we have personal representatives in each hospital, we keep direct contact with clinics all over the world. So, the efficiency and responsiveness of the treatment services are vital in cancer treatment.

What are the best proton beam centers in the world?

Proton beam therapy is a specific type of radiation therapy available in a limited number of medical entities worldwide. Compared to conventional radiation therapy centers, PBT ones are spread most in highly developed countries or countries that have invested greatly in the medical industry.

There are specific features that characterize PBT, explaining its uniqueness and expensiveness:

• the need for specialized equipment for the therapy;

• is spread in countries that possess advanced facilities at hospitals;

• is done by a qualified medical provider under the specific conditions and who is experienced enough to perform pediatric tumors, tumors near critical organs, and deals with specific cancer types;

• can not be covered by all insurance plans.

🌍 Spain

In recent years, Spain has made significant investments in establishing domestic facilities for PBT in cancer treatment. Some Spanish clinics became among the first institutions to offer this treatment, having treated over 1,000 patients annually since 2020. Spanish hospitals made significant advancements in cancer treatment, offering patients access to cutting-edge proton therapies.

🏥 Proton Therapy Centre Quironsalud (Madrid, Spain)

This is the first clinic in Spain that offers advanced PBT. It's equipped with high-end Varian ProBeam® technology, ensuring precise and efficient treatment for sensitive tumors. The Centre is also a part of a fully integrated cancer care facility, offering various diagnostics, treatment plans, and post-treatment follow-ups under one roof. The clinic also prioritizes pediatric cancer care, reducing side effects for children.

The clinic offers a complete package for proton beam therapy (PBT) with the cost of $47,200 that includes the following medical procedures:

• proton-beam therapy;

• complete blood count with cancer markers and a proteinogram;

• head MRI;

• MRI of one area;

• 3D CT scan.

This offer includes the cost of 25 proton therapy sessions, all needed diagnostic procedures, doctor consultations related to proton therapy, and after-treatment healthcare.

The hospital also offers PBT for cancers of different areas at the following price rate.

🏥 Centro Médico Teknon (Barcelona, Spain)

This proton therapy clinic is considered digital, as doctors apply various advanced technologies to perform surgeries and check-ups accurately. 

Spanish oncologists follow the high American standards developed at Memorial Sloan Kettering Cancer Center to provide patients with the latest technologies and precise treatment plans.

They utilize such equipment to treat tumors without damaging healthy tissues and organs:

• 3D-CRT (three-dimensional conformal radiotherapy) device to irradiate the tumor, located close to the vital organs without any damage;

• Novalis linear accelerator that adapts to the tumor size and shape.

The price for PBT here ranges from $26,200 to $47,200.

🌍 Turkey

Turkey is among the most popular countries for undergoing PBT. The main reason is its affordability and availability of high-quality medical services. Turkey attracts patients worldwide due to its combination of advanced medical facilities, affordable services, and accessibility for international patients.

Daily, over 1,200 patients trust their health to the clinics in the country.

Up to 50-70% of treatment expenses can be saved compared to the prices of US and UK clinics, which can reach up to $150,000 and higher. Moreover, Turkish hospitals are JCI-accredited, which means they follow high standards of care and safety.

🏥 Anadolu Medical Center (Istanbul, Turkey)

The hospital is one of the most authoritative medical entities in Turkey due to its high expertise and adherence to the American healthcare standards. It is also a partner of the Johns Hopkins Hospital. Almost 1,800 patients chose the clinic for oncology treatment.

Oncology is one of the leading specialties at the hospital. Patients are treated using the latest equipment for precise diagnosis, such as Truebeam for radiation therapy and Flash-CT, PET-CT, and MRI 3 Tesla devices for accurate tumor screening.

🏥 Memorial Şişli Hospital (Istanbul, Turkey)

The oncology Department's doctors provide treatment according to the international NCCN (National Comprehensive Cancer Network) and ESMO (European Society for Medical Oncology) protocols.

The hospital offers the following services: radiotherapy, chemotherapy, surgical interventions, and targeted drug application to destroy cancer cells. It also uses the latest radiotherapy devices, TrueBeam STx and IMRT.

🌍 Israel

Israeli medical centers combine cutting-edge technologies with a multidisciplinary approach to cancer treatment. Proton beam radiation centers are equipped with the latest proton therapy systems, like the FDA-approved P-Cure proton therapy system, while oncologists use individualized treatment plans.

🏥 Sourasky Medical Center (Ichilov) (Tel Aviv, Israel)

It's ranked among the Top 10 proton therapy centers for medical tourists worldwide. Its strongest specialties are oncology, onco-hematology, neurosurgery, and rehabilitation. Moreover, this is the first proton therapy center in Israel.

There are the following ways to diagnose and treat cancer: PET CT, Flash CT scan and the FoundationOne CDx diagnostic test that detects 324 genes that can cause the development of malignant solid tumors. Additionally, the hospital has 90% of the average success rate of oncology treatment.

Prices for PBT for treating various cancer types in Israel range from around $100,000.

🌍 Republic of Korea

The National Cancer Center operates proton beam cancer centers in Korea. The institution strives to improve national health by reducing the incidence and mortality of cancer through thorough research, patient care, education and training, and support for national cancer treatment programs.

🏥 Samsung Medical Center

Samsung Proton Therapy Center is among the most innovative. During proton therapy, doctors can scan the body to obtain a precise image and characteristics of a tumor. 

An automated robotic bed regulates the patient's position during the procedure, making the treatment more precise. The clinic has the highest indexes in the world for treating stomach, colorectal, lung, and liver cancers.

The average cost of PBT in the Republic of Korea ranges from about $43,500.

🌍 The Czech Republic

Being among the best proton therapy centers in the Czech Republic and Europe, The Proton Therapy Center in Prague provides comprehensive medical support in cancer treatment of the main organs like the breast, neck and head, brain, and liver, also offering proton beam therapy for prostate cancer locations that distinguish among other European PBT clinics.

🏥 Proton Therapy Center (Prague)

This is Europe's largest center for proton beam therapy, attracting international patients. The Center specializes in PBT, using advanced technologies and following international standards.

It uses Ion Beam Applications, which is one of the world's leading radiology equipment providers. The clinic is also certified by SAKCR (Czech United Accreditation Commission) to conform to the standards of high-quality and safe medical services in the Czech Republic.

The Center performs clinical research proving the high success rate of cancer treatments since 2021.

In the Czech Republic, the average cost for PBT is:

• for the procedure overall—$52,500;

• for prostate cancer—around $47,000;

• for brain cancer treatment—$57,000.

You can receive more detailed consultations and take a diagnostic or treatment course at the chosen proton beam center by contacting Bookimed patient support. 

It can be pretty challenging to schedule an appointment at these leading PBT centers with a highly qualified doctor on your own. Some issues can occur when contacting the needed clinic or long queues to arrange a consultation or procedure. 

➡️ Therefore, Bookimed can be handy for getting medical help online or arranging offline appointments with the doctor you need. The medical coordinator will give all the necessary information regarding PBT at any clinic.

What is the price for proton therapy in the leading countries?

The average price for PBT for prostate and breast cancer

📌 The average cost of PBT across Turkish beam locations is:

• PBT generally—$21,000-$65,000;

• PBT for breast cancer—around $60,000;

• PBT for prostate cancer—$25,000-$60,000.

📌 In the Czech Republic, the average cost for PBT is:

• for the procedure overall—$52,500;

• for prostate cancer—around $47,000;

• for brain cancer treatment—$57,000.

📌 The price tag for PBT in Spain is the following:

• PBT generally—$47,000-$74,000;

• PBT for prostate cancer—$42,000-$70,000;

• PBT for breast cancer—$26,000-$70,000.

📌 Speaking about Israeli PBT clinics, cancer treatment services there fluctuate around $100,000.

📌 What about the Korean hospitals that offer proton therapy? The average price for the procedure starts around $50,000.

These countries provide beneficial offers that include complete packages with treatment plans, apply innovative technologies, and have advanced medical facilities to perform this therapy on a high level.

➡️ Bookimed's partner clinics offers patients all-inclusive cancer treatment packages. As usual, these packages are affordable, lower than the cost of each service separately. What's more, there are no extra fees, as all prices are the same as those offered by our partner clinics.

What is the success rate for PBT in the best proton therapy centers?

Overall, the success rate of PBT varies depending on the cancer type and stage. Although, it has shown promising outcomes for many types of cancers. Here's a brief overview:

• Pediatric cancers—85-90% survival rates.

• Prostate cancer—a 5-year survival rate of 90-95% for localized prostate cancer.

• Head and neck cancers—80-85%, with a low risk of critical structures damage such as salivary glands and lower toxicity. In the case of a brain tumor, a 3-year survival rate reaches approximately 60%.

• Lung cancer—a 2-year survival rate of 40-50%, depending on the stage and type.

• Breast cancer—a study reported that patients who received proton therapy after a mastectomy for non-metastatic breast cancer had an overall 3-year survival rate of 97.2%.

How Bookimed can help you choose the best PBT center?

It can be challenging for patients to choose the proper PBT center, so Bookimed medical coordinators will help them make the right choice. As a trusted global medical tourism platform, we help patients worldwide find the best clinic and doctor to treat any health condition.

You have a unique opportunity to get the following services:

✅ Submit a request and highlight your problem.

✅ A medical coordinator calls you back after studying your issue.

✅ The coordinator chooses the best PBT center and doctor.

✅ You choose the treatment plan while your medical coordinator arranges the medical journey.

✅ You stay in touch 24/7 with us throughout the treatment.

✅ Bookimed follows your treatment process and stays in touch even after your return.

✅ The medical coordinator will help solve unforeseen problems.

References:

1. Cancer screening. Tel Aviv Medical Clinic. Source: https://tamc.co.il/en/services-en/cancer-screening/ 

2. Prostate Cancer. Results of the Prague Proton Center. Source: https://www.ptc.cz/en/what-we-treat/prostate/prostate-cancer/results-of-the-prague-proton-center/?utm_source=chatgpt.com 

3. Heike Thomas, Beate Timmermann. Paediatric proton therapy. International Journal of Radiology, Radiation Oncology and All Related Sciences. 2020 Feb 14;93(1107):20190601.

4. Is Proton Therapy Safer than Traditional Radiation? National Cancer Institute. Source: https://www.cancer.gov/news-events/cancer-currents-blog/2020/proton-therapy-safety-versus-traditional-radiation#:~:text=After%203%20years%2C%2046%25%20of,still%20alive%20after%203%20years. 

5. Proton Therapy for Breast Cancer. Source: https://www.healthline.com/health/breast-cancer/proton-therapy-for-breast-cancer?utm_source=chatgpt.com#what-is-it 

6. Yao-Yu Wu, MD, Kang-Hsing Fan. Proton therapy for prostate cancer: current state and future perspectives. British Journal of Radiology, Volume 95, Issue 1131, 1 March 2022.